SCHEMBL101706

SCHEMBL101706

COc1cn(C)c(=S)n(N)c1=O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MPO P05164 1/20 0.41
XDH P47989 1/20 0.41
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
BRD4 O60885 10/20 0.33
BRD9 Q9H8M2 8/20 0.33
BRD2 P25440 5/20 0.33
BRD7 Q9NPI1 5/20 0.33
GAA P10253 2/20 0.33
S100B P04271 1/20 0.33
ALDH1A1 P00352 2/20 0.31
DDAH1 O94760 1/20 0.31
KDM4E B2RXH2 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29048928 0.81 S100B (0.38) MPOXDHLMNAMAPTCYP2C9
SCHEMBL2384938 0.78 BRD4 (0.35) MPOXDHLMNAMAPTCYP2C9
SCHEMBL25980029 0.68 ERN1 (0.47) LMNAMAPTCYP2C9GAAS100B
SCHEMBL16921627 0.63 MAPT (0.36) LMNAMAPTCYP2C9BRD4BRD9
SCHEMBL15807133 0.63 MAPT (0.43) MPOXDHLMNAMAPTGAA
SCHEMBL6932284 0.62 ERN1 (0.36) LMNAMAPTCYP2C9BRD4S100B
SCHEMBL18163876 0.59 BRD4 (0.42) LMNAMAPTCYP2C9BRD4BRD9
SCHEMBL17372112 0.59 GRIN2D (0.42) LMNAMAPTCYP2C9ALDH1A1KDM4E
SCHEMBL2730975 0.58 MPO (1.00) MPOXDHMAPTGAAALDH1A1
SCHEMBL16651423 0.58 BRD4 (0.47) LMNAMAPTCYP2C9BRD4BRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1085 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3889611-B1 COMPOSITIONS AND METHODS FOR PERFORMING METHYLATION DETECTION ASSAYS EXACT SCIENCES CORP (US) 2026-05-27 EP disclosed
US-20260132421-A1 CHARACTERIZATION OF IMPURITIES IN ADENO-ASSOCIATED VIRUS (AAV) SAMPLES AND FORMULATION COMPOSITIONS TO STABILIZE AAV REGENERON PHARMACEUTICALS, INC. (US) 2026-05-14 US disclosed
US-12606814-B2 Oligonucleotide probes and uses thereof CARIS SCIENCE, INC. (US) 2026-04-21 US disclosed
US-20260103762-A1 COMPOSITIONS AND METHODS FOR PERFORMING METHYLATION DETECTION ASSAYS EXACT SCIENCES CORP (US) 2026-04-16 US disclosed
US-20260092331-A1 METHODS AND COMPOSITIONS FOR CHARACTERIZING BLADDER CANCER UNIV OSLO HF (NO) 2026-04-02 US disclosed
US-20260092305-A1 ISOLATION OF NUCLEIC ACIDS EXACT SCIENCES CORP (US) 2026-04-02 US disclosed
US-20260078383-A1 RNA NANOSTRUCTURES AND METHODS OF MAKING AND USING RNA NANOSTRUCTURES UNIV ARIZONA STATE (US) 2026-03-19 US disclosed
US-20260077004-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CARDIAC DISORDERS UNIVERSITY OF MASSACHUSETTS (US) 2026-03-19 US disclosed
US-12577627-B2 Selective detection of different dengue virus RNA serotypes using tandem toehold-mediated displacement reactions ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONE STATE UNIVERSITY (US) 2026-03-17 US disclosed
EP-4189086-B1 PURIFICATION OF SULFONATED DNA EXACT SCIENCES CORP (US) 2026-03-11 EP disclosed
US-20030224055-A1 Compositions and processes for inhibiting gene expression using polynucleotides ROCHE MADISON INC. 2003-12-04 US disclosed
WO-2003099228-A2 COMPOSITIONS AND PROCESSES FOR INHIBITING GENE EXPRESSION USING POLYNUCLEOTIDES MIRUS CORPORATION (US) 2003-12-04 WO disclosed
WO-2003100439-A2 RECEPTOR AND SCREENING METHODS UNIVERSITY OF SHEFFIELD (GB) 2003-12-04 WO disclosed
WO-2003099225-A2 COMPOSITIONS FOR DELIVERING NUCLEIC ACIDS TO CELLS MIRUS CORPORATION (US) 2003-12-04 WO disclosed
US-20030220289-A1 Compositions for delivering nucleic acids to cells ROCHE MADISON INC. 2003-11-27 US disclosed
WO-2003080794-A2 INHIBITION OF RNA FUNCTION BY DELIVERY OF INHIBITORS TO ANIMAL CELLS MIRUS CORPORATION (US) 2003-10-02 WO disclosed
WO-2003068961-A2 METHOD TO MODIFY DIFFERENTIATION OF PLURIPOTENTIAL STEM CELLS AXORDIA LIMITED (GB) 2003-08-21 WO disclosed
US-20030143204-A1 Inhibition of RNA function by delivery of inhibitors to animal cells LEWIS DAVID L (US) 2003-07-31 US disclosed
CN-1433431-A Interleukin-1 receptor antagonist-like molecules and uses thereof AMGEN INC (US) 2003-07-30 CN disclosed
WO-2003008573-A2 SILENCING OF GENE EXPRESSION BY SIRNA MILNER ANNE JOSEPHINE (GB) 2003-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577627-B2 Selective detection of different dengue virus RNA serotypes using tandem toehold-mediated displacement reactions DDX41, DDX5, DDX6 MPO 2381/4885XDH 1701/4885LMNA 1406/4885
US-12606814-B2 Oligonucleotide probes and uses thereof CD63, FLT4, NCL MPO 2018/4885XDH 3901/4885LMNA 1587/4885
US-20260092305-A1 ISOLATION OF NUCLEIC ACIDS POLRMT, POLI, FUS MPO 4154/4885XDH 2630/4885LMNA 365/4885
US-20260092331-A1 METHODS AND COMPOSITIONS FOR CHARACTERIZING BLADDER CANCER DNMT3A, DNMT3L, INMT MPO 477/4885XDH 338/4885LMNA 770/4885
US-20260103762-A1 COMPOSITIONS AND METHODS FOR PERFORMING METHYLATION DETECTION ASSAYS SEPTIN2, DNMT3B, DNMT1 MPO 4125/4885XDH 2551/4885LMNA 1297/4885
US-20260132421-A1 CHARACTERIZATION OF IMPURITIES IN ADENO-ASSOCIATED VIRUS (AAV) SAMPLES AND FORMULATION COMPOSITIONS TO STABILIZE AAV ADAR, SLC28A2, SLC12A2 MPO 3979/4885XDH 2659/4885LMNA 585/4885
US-20260078383-A1 RNA NANOSTRUCTURES AND METHODS OF MAKING AND USING RNA NANOSTRUCTURES PDCD1, TIA1, NSUN2 MPO 2495/4885XDH 3163/4885LMNA 491/4885
US-20030143204-A1 Inhibition of RNA function by delivery of inhibitors to animal cells NSUN2, RNASE1, NSUN3 MPO 3832/4885XDH 2650/4885LMNA 604/4885
US-20260077004-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CARDIAC DISORDERS KCNH2, KCNH3, KCNQ1 MPO 4705/4885XDH 2378/4885LMNA 168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.