Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456726 | 0.81 | NR1H4 (0.38) | NR1H4ACE2PARP15PARP10PARP2 | |
| SCHEMBL702949 | 0.81 | NR1H4 (0.38) | NR1H4ACE2PARP15PARP10PARP2 | |
| SCHEMBL5859592 | 0.75 | NR1H4 (0.35) | NR1H4PARP15PARP10PARP2MAP4K4 | |
| SCHEMBL216951 | 0.73 | PARP15 (0.32) | PARP15PARP10PARP2 | |
| SCHEMBL2456728 | 0.72 | DRD2 (0.44) | NR1H4PARP15PARP10PARP2 | |
| SCHEMBL5859588 | 0.71 | PARP15 (0.36) | NR1H4PARP15PARP10PARP2TSHR | |
| SCHEMBL25277718 | 0.71 | NR1H4 (0.43) | NR1H4 | |
| SCHEMBL3722748 | 0.70 | GRIK1 (0.46) | TSHR | |
| SCHEMBL218978 | 0.69 | DRD2 (0.45) | PARP15PARP10PARP2 | |
| SCHEMBL6532504 | 0.67 | RARB (0.33) | ACE2RXRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373339-B1 | SHAPE MEMORY STYRENE COPOLYMER | JOHNSON & JOHNSON VISION CARE (US) | 2006-01-18 | — | — | EP | claimed |