Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HNF4A | P41235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109672 | 0.75 | ALDH1A1 (0.35) | RARBRARGRARARXRARXRB | |
| SCHEMBL29242763 | 0.70 | ACE2 (0.40) | ACE2RXRAKDM4EHNF4A | |
| SCHEMBL6049060 | 0.67 | NR1H4 (0.38) | ACE2RXRAKDM4E | |
| SCHEMBL11701349 | 0.67 | KDM4E (0.49) | ACE2KDM4E | |
| SCHEMBL5799937 | 0.67 | ALDH1A1 (0.37) | RARBRARGRARARXRARXRB | |
| SCHEMBL788898 | 0.65 | ACE2 (0.44) | ACE2KDM4E | |
| SCHEMBL4274180 | 0.64 | KDM4E (0.43) | ACE2KDM4E | |
| SCHEMBL8054469 | 0.64 | ACE2 (0.50) | ACE2RXRAKDM4E | |
| SCHEMBL10531665 | 0.64 | KDM1A (0.41) | RARBRARGACE2RARAKDM1A | |
| SCHEMBL3651606 | 0.64 | HTT (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373340-B1 | SHAPE MEMORY POLYMER OR ALLOY OPHTHALMIC LENS MOLD AND METHODS OF FORMING OPHTHALMIC PRODUCTS | JOHNSON & JOHNSON VISION CARE (US) | 2005-10-19 | — | — | EP | claimed |