SCHEMBL6049077

SCHEMBL6049077

C/N=c1\scc(CCl)n1C

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 1/20 0.39
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3528466 1.00 CXCR4 (0.39) CXCR4ALDH1A1GAA
Hydrochloric Acid SCHEMBL3894282 0.98 CXCR4 (0.39) CXCR4ALDH1A1GAA
SCHEMBL3894363 0.70
Hydrochloric Acid SCHEMBL3909331 0.64 PDE4D (0.34) ALDH1A1
Hydrochloric Acid SCHEMBL3900671 0.62
Hydrochloric Acid SCHEMBL3901555 0.62 ALDH1A1 (0.40) ALDH1A1
Hydrochloric Acid SCHEMBL3901551 0.62 ALDH1A1 (0.40) ALDH1A1
Hydrochloric Acid SCHEMBL3908786 0.59
Hydrochloric Acid SCHEMBL3908782 0.59
Hydrochloric Acid SCHEMBL4823268 0.58 GPR84 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1669352-A1 THIAZOLINE DERIVATIVE AND USE OF THE SAME Takeda Pharmaceutical Company Limited (JP) 2006-06-14 EP disclosed