Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326405 | 0.79 | TSHR (0.43) | TSHRACHEALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL3188779 | 0.78 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL4480 | 0.77 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL3127305 | 0.77 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL29357701 | 0.77 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL1991572 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL2857411 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| Bromide SCHEMBL3688252 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL18425305 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL10705496 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034093-B2 | Catalysts for olefin polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-04-25 | — | — | US | disclosed |
| US-20050119429-A1 | Catalysts for olefin polymerization | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2005-06-02 | — | — | US | disclosed |
| WO-2003078478-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-25 | — | — | WO | disclosed |
| US-5180848-A | Synthesis of phosphinoacetic acids | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| US-5157153-A | Reacting alkyl ethynyl ether or monohaloacetaldehyde acetal with alkali metal base, then with halodihydrocarbylphosphine; adding mineral acid, hydrolyzing | PHILLIPS PETROLEUM COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119429-A1 | Catalysts for olefin polymerization | PPIP5K2, ETFA, PPOX | TSHR 4566/4885ACHE 3464/4885ALDH1A1 4088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.