Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.58 |
| ▸ | CES2 | O00748 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600679 | 0.88 | MEN1 (0.64) | CES1CES2KMT2AMEN1MAPT | |
| SCHEMBL10444453 | 0.84 | MAPT (0.58) | CES1CES2KMT2AMEN1MAPT | |
| SCHEMBL25308457 | 0.78 | SRD5A2 (0.59) | CES1CES2KMT2AMEN1MAPT | |
| SCHEMBL10338999 | 0.78 | FNTA (0.56) | CES1CES2KMT2AMEN1MAPT | |
| SCHEMBL11400746 | 0.77 | RAB9A (0.61) | KMT2AMAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL28598267 | 0.77 | L3MBTL1 (0.74) | CES1CES2KMT2AMEN1MAPT | |
| Benzil SCHEMBL8339350 | 0.77 | CES2 (0.64) | CES1CES2KMT2AMEN1MAPT | |
| SCHEMBL15180810 | 0.76 | CES2 (1.00) | CES1CES2MAPTCYP3A4TDP1 | |
| SCHEMBL180411 | 0.76 | CES2 (1.00) | CES1CES2MAPTCYP3A4TDP1 | |
| SCHEMBL5217028 | 0.75 | CES1 (0.54) | CES1CES2KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644435-A2 | STABILIZING COMPOSITION FOR CHLORINE-CONTAINING POLYMERS | ARKEMA (FR) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005005530-A2 | STABILIZING COMPOSITION FOR CHLORINE-CONTAINING POLYMERS | ARKEMA (FR) | 2005-01-20 | — | — | WO | disclosed |