Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 6/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 6/20 | 0.32 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050976 | 0.80 | EPHX2 (0.39) | EDNRAALDH1A1 | |
| SCHEMBL6050991 | 0.73 | SMN1; SMN2 (0.41) | KMT2AALDH1A1 | |
| SCHEMBL4984754 | 0.70 | MEN1 (0.36) | MEN1KMT2AP2RX7ALDH1A1ATM | |
| SCHEMBL6050958 | 0.70 | ATM (0.39) | MEN1KMT2AALDH1A1ATM | |
| SCHEMBL2836371 | 0.67 | MEN1 (0.44) | MEN1KMT2AP2RX7ALDH1A1ATM | |
| SCHEMBL6050988 | 0.64 | MEN1 (0.40) | MEN1KMT2AP2RX7ALDH1A1ATM | |
| SCHEMBL6050977 | 0.64 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL4979060 | 0.63 | — | — | |
| SCHEMBL4984759 | 0.63 | ALDH1A1 (0.38) | MEN1KMT2AGAAALDH1A1ATM | |
| SCHEMBL27500052 | 0.63 | P2RX7 (0.51) | MEN1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505945-A4 | SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2006-11-22 | — | — | EP | disclosed |
| EP-1505945-A2 | SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2004043339-A2 | SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |