Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231426 | 0.85 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL2944734 | 0.81 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL30389113 | 0.81 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29011955 | 0.81 | NPC1 (0.38) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL4436624 | 0.80 | NPC1 (0.37) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29501855 | 0.79 | CA2 (0.52) | NPC1RAB9ALMNAPOLBTSHR | |
| SCHEMBL424271 | 0.79 | CA2 (0.52) | NPC1RAB9ALMNAPOLBTSHR | |
| SCHEMBL29053348 | 0.77 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL6035514 | 0.76 | NPC1 (0.36) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL8024417 | 0.75 | CA2 (0.41) | NPC1RAB9ALMNAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680463-A2 | STABILIZER COMPOSITIONS FOR HALOGEN CONTAINING POLYMERS | Ciba SC Holding AG (CH) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005049715-A2 | STABILIZER COMPOSITIONS FOR HALOGEN CONTAINING POLYMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-06-02 | — | — | WO | disclosed |