SCHEMBL2944734

SCHEMBL2944734

CC(C)(C)CC(C)(C)c1cccc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.40
RAB9A P51151 5/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 3/20 0.36
ATM Q13315 1/20 0.35
KDM4E B2RXH2 6/20 0.33
CA2 P00918 1/20 0.33
SHBG P04278 1/20 0.33
HPGD P15428 4/20 0.33
ALDH1A1 P00352 4/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 3/20 0.31
MEN1 O00255 2/20 0.31
ALOX15 P16050 2/20 0.31
CASP1 P29466 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 2/20 0.31
APAF1 O14727 1/20 0.31
TP53 P04637 1/20 0.31
CASP7 P55210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30389113 1.00 NPC1 (0.40) NPC1RAB9ALMNAPOLBATM
SCHEMBL4387585 0.89 NPC1 (0.37) NPC1RAB9ALMNAPOLBATM
SCHEMBL2231426 0.87 NPC1 (0.41) NPC1RAB9ALMNAPOLBATM
SCHEMBL28894056 0.86 NPC1 (0.38) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL6035514 0.85 NPC1 (0.36) NPC1RAB9ALMNAPOLBATM
SCHEMBL4436624 0.84 NPC1 (0.37) NPC1RAB9ALMNAPOLBATM
SCHEMBL29501855 0.83 CA2 (0.52) NPC1RAB9ALMNAPOLBATM
SCHEMBL424271 0.83 CA2 (0.52) NPC1RAB9ALMNAPOLBATM
SCHEMBL928616 0.82 NPC1 (0.38) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL29371482 0.82 NPC1 (0.44) NPC1RAB9ALMNAPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7045200-B2 White, UV-stabilized film made from a crystallizable thermoplastic MITSUBISHI POLYESTER FILM GMBH (DE) 2006-05-16 US claimed
US-20260008766-A1 EPISULFIDE COMPOUND AND OPTICAL MATERIAL COMPOSITION THEREOF Efirm New Material Co., Ltd. (CN) 2026-01-08 US disclosed
WO-2024170002-A1 NOVEL EPISULFIDE COMPOUND AND OPTICAL MATERIAL COMPOSITION THEREOF 益丰新材料股份有限公司 2024-08-22 WO disclosed
CN-116143767-B Episulfide compound, composition for optical material, optical material and application 益丰新材料股份有限公司 2024-02-23 CN disclosed
EP-4301810-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING ORGANIC MATERIALS, STABILIZER COMPOSITION, MASTER BATCH, COMPOSITION, MOLDING COMPOUND FOR MOLDINGS, PROCESS FOR OXIDATIVE, THERMAL AND ACTINIC STABILIZATION OF A THERMOPLASTIC, AND USE OF A COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-01-10 EP disclosed
CN-116478124-B Novel episulfide compound and optical material composition thereof 益丰新材料股份有限公司 2023-12-01 CN disclosed
CN-116478148-B Episulfide compound and application thereof 益丰新材料股份有限公司 2023-10-13 CN disclosed
CN-116874924-A Plastic for automotive interior and preparation method thereof 上海瀚氏科技集团有限公司 2023-10-13 CN disclosed
CN-116836156-A Compound and preparation method thereof, optical material composition and curing composition 益丰新材料股份有限公司 2023-10-03 CN disclosed
CN-116478124-A Novel episulfide compound and optical material composition thereof 益丰新材料股份有限公司 2023-07-25 CN disclosed
CN-1699446-A Solution casting method FUJI PHOTO FILM CO LTD (JP) 2005-11-23 CN disclosed
WO-2004108799-A1 NOVEL SURFACE-ACTIVE POLYSILOXANE PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-12-16 WO disclosed
EP-1327662-A1 Stabiliser combinations for chlorinated polymers Crompton Vinyl Additives GmbH (DE) 2003-07-16 EP disclosed
EP-1274780-A1 COMPOSITIONS CONTAINING POLYCARBONATE Bayer Aktiengesellschaft (DE) 2003-01-15 EP disclosed
WO-2001074935-A1 COMPOSITIONS CONTAINING POLYCARBONATE BAYER AKTIENGESELLSCHAFT (DE) 2001-10-11 WO disclosed
EP-1032576-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES Ciba SC Holding AG (CH) 2000-09-06 EP disclosed
EP-1027348-A1 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLES USED AS U.V. STABILISERS GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 2000-08-16 EP disclosed
WO-1999043666-A1 PHOTOCHROMATIC COMPOSITIONS ENDOWED WITH LIGHT FATIGUE RESISTANCE AND PHOTOCHROMATIC ARTICLES CONTAINING THEM GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1999-09-02 WO disclosed
WO-1999023093-A1 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLES USED AS U.V. STABILISERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1999-05-14 WO disclosed
WO-1998038195-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008766-A1 EPISULFIDE COMPOUND AND OPTICAL MATERIAL COMPOSITION THEREOF LATS1, LATS2, TST NPC1 4367/4885RAB9A 3058/4885LMNA 4519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.