Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052089 | 0.82 | PDE2A (0.49) | CCNKCDK12 | |
| SCHEMBL6051960 | 0.79 | CDK1 (0.46) | CDK1CCNB1CCNKCDK12TDP1 | |
| SCHEMBL6051992 | 0.77 | TDP1 (0.39) | MAPK1TDP1 | |
| SCHEMBL6052078 | 0.77 | TDP1 (0.43) | TSHRMAPK1TDP1 | |
| SCHEMBL6051967 | 0.76 | CDK1 (0.42) | CDK1CCNB1CCNKCDK12TDP1 | |
| SCHEMBL6051982 | 0.72 | CDK1 (0.38) | CDK1CCNB1CCNKCDK12 | |
| SCHEMBL6023263 | 0.72 | PDE2A (0.44) | — | |
| SCHEMBL6052136 | 0.71 | CDK1 (0.38) | CDK1CCNB1CCNKCDK12 | |
| SCHEMBL7459663 | 0.69 | ADA (0.69) | TSHR | |
| SCHEMBL7440929 | 0.69 | PDE2A (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229242-A1 | Composition comprising a pulmonary surfactant and a pde2 inhibitor | ALTANA PHAZMA AG (DE) | 2006-10-12 | — | — | US | claimed |
| EP-1660132-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE2 INHIBITOR | ALTANA Pharma AG (DE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005021037-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE2 INHIBITOR | ALTANA PHARMA AG (DE) | 2005-03-10 | — | — | WO | claimed |
| US-20060229242-A1 | Composition comprising a pulmonary surfactant and a pde2 inhibitor | ALTANA PHAZMA AG (DE) | 2006-10-12 | — | — | US | disclosed |
| EP-1660132-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE2 INHIBITOR | ALTANA Pharma AG (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005021037-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE2 INHIBITOR | ALTANA PHARMA AG (DE) | 2005-03-10 | — | — | WO | disclosed |