Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052081 | 0.95 | PDE2A (0.42) | PDE2AALDH1A1CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL6051992 | 0.89 | TDP1 (0.39) | PDE2AALDH1A1CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL6052078 | 0.84 | TDP1 (0.43) | ALDH1A1CYP3A4CYP2D6SMN1; SMN2POLB | |
| SCHEMBL6023204 | 0.81 | PDE2A (0.51) | PDE2ARNASEH1 | |
| SCHEMBL6023837 | 0.81 | PDE2A (0.51) | PDE2ARNASEH1 | |
| SCHEMBL6052089 | 0.78 | PDE2A (0.49) | PDE2ARNASEH1 | |
| SCHEMBL6023263 | 0.78 | PDE2A (0.44) | PDE2ARNASEH1 | |
| SCHEMBL7440929 | 0.77 | PDE2A (0.54) | PDE2ARNASEH1 | |
| SCHEMBL359546 | 0.74 | PDE2A (0.51) | PDE2AALDH1A1SMN1; SMN2POLBRNASEH1 | |
| SCHEMBL6024137 | 0.73 | PDE2A (0.42) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229242-A1 | Composition comprising a pulmonary surfactant and a pde2 inhibitor | ALTANA PHAZMA AG (DE) | 2006-10-12 | — | — | US | claimed |