Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744374 | 0.85 | MAPT (0.67) | MAPTGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6052293 | 0.84 | MAPT (0.72) | MAPTGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL17450416 | 0.83 | ALDH1A1 (0.54) | MAPTGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6052282 | 0.83 | MAPT (0.55) | MAPTGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2448297 | 0.81 | MAPT (0.50) | MAPTGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL17631428 | 0.80 | GAA (0.47) | MAPTGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6052248 | 0.80 | MAPT (0.47) | MAPTGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6052308 | 0.79 | GFER (0.60) | MAPTGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL17264117 | 0.79 | ALDH1A1 (0.50) | MAPTGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL77976 | 0.77 | L3MBTL3 (0.59) | MAPTGAAALDH1A1HTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015218-B1 | Amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |