Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13313190 | 0.81 | TDP1 (0.63) | TDP1L3MBTL1CALM1IGF1RALOX15 | |
| SCHEMBL11442816 | 0.81 | CALM1 (0.54) | S1PR1S1PR3CALM1IGF1RALOX15 | |
| SCHEMBL4943606 | 0.80 | LPAR1 (0.55) | S1PR1S1PR3L3MBTL1LPAR3LPAR1 | |
| SCHEMBL7692985 | 0.80 | LPAR1 (0.55) | S1PR1S1PR3L3MBTL1LPAR3LPAR1 | |
| SCHEMBL26908448 | 0.80 | LPAR1 (0.55) | S1PR1S1PR3L3MBTL1LPAR3LPAR1 | |
| SCHEMBL29758247 | 0.80 | LPAR1 (0.55) | S1PR1S1PR3L3MBTL1LPAR3LPAR1 | |
| SCHEMBL10459319 | 0.80 | LPAR1 (0.55) | S1PR1S1PR3L3MBTL1LPAR3LPAR1 | |
| SCHEMBL2437208 | 0.80 | LPAR1 (0.55) | S1PR1S1PR3L3MBTL1LPAR3LPAR1 | |
| SCHEMBL10533195 | 0.80 | LPAR1 (0.55) | S1PR1S1PR3L3MBTL1LPAR3LPAR1 | |
| SCHEMBL26908453 | 0.80 | LPAR1 (0.55) | S1PR1S1PR3L3MBTL1LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060250-B2 | Diagnostic imaging contrast agents with extended blood retention | EPIX PHARMACEUTICALS, INC. (US) | 2006-06-13 | — | — | US | disclosed |
| US-20040202613-A1 | Chelate compounds | EPIX MEDICAL, INC., A DELAWARE CORPORATION | 2004-10-14 | — | — | US | disclosed |
| US-20020164289-A1 | Medical diagnosis | CITIZENS BANK, N.A. | 2002-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020164289-A1 | Medical diagnosis | FABP1, B2M, MB | S1PR1 898/4885S1PR3 780/4885TDP1 3359/4885 |
| US-20040202613-A1 | Chelate compounds | FABP1, BHMT, FABP3 | S1PR1 1043/4885S1PR3 769/4885TDP1 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.