Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10703075 | 0.81 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1266941 | 0.81 | ALKBH5 (0.49) | KDM4EALDH1A1 | |
| SCHEMBL10400766 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL692667 | 0.78 | MAPT (0.52) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8990040 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11025769 | 0.78 | KDM4E (0.31) | KDM4EALDH1A1MAPT | |
| SCHEMBL9342365 | 0.78 | — | — | |
| SCHEMBL9338763 | 0.77 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPT | |
| SCHEMBL10703638 | 0.77 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPT | |
| SCHEMBL9505993 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272223-B1 | THERAPEUTIC AND DIAGNOSTIC LIGAND SYSTEMS COMPRISING TRANSPORT MOLECULE BINDING PROPERTIES AND MEDICAMENTS CONTAINING THE SAME | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-05-31 | — | — | EP | disclosed |
| EP-1272223-A1 | THERAPEUTIC AND DIAGNOSTIC LIGAND SYSTEMS COMPRISING TRANSPORT MOLECULE BINDING PROPERTIES AND MEDICAMENTS CONTAINING THE SAME | KTB Tumorforschungsgesellschaft mbH (DE) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001068142-A1 | THERAPEUTIC AND DIAGNOSTIC LIGAND SYSTEMS COMPRISING TRANSPORT MOLECULE BINDING PROPERTIES AND MEDICAMENTS CONTAINING THE SAME | KTB TUMORFORSCHUNGSGESELLSCHAFT MBH (DE) | 2001-09-20 | — | — | WO | disclosed |