Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 4/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990086 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KDM4EL3MBTL1CTSAMEN1 | |
| SCHEMBL1266941 | 0.86 | ALKBH5 (0.49) | ALDH1A1KDM4EALKBH5CTSAMEN1 | |
| SCHEMBL692667 | 0.80 | MAPT (0.52) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL8990138 | 0.80 | ATAD2 (0.36) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10400766 | 0.78 | KDM4E (0.33) | ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6053229 | 0.78 | KDM4E (0.30) | ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL11139711 | 0.77 | KDM4E (0.40) | ALDH1A1KDM4EL3MBTL1ALKBH5CTSA | |
| SCHEMBL11140976 | 0.77 | KDM4E (0.42) | ALDH1A1KDM4EL3MBTL1ALKBH5CTSA | |
| SCHEMBL11121976 | 0.76 | ALKBH5 (0.50) | ALDH1A1KDM4EALKBH5CTSAMAPT | |
| SCHEMBL10810956 | 0.75 | ALDH1A1 (0.60) | ALDH1A1KDM4EALKBH5CTSAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35359-E | Amine salts of azo pigments based on pyrazolone derivatives | CIBA-GEIGY CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0241413-B1 | AMINE SALTS OF AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | disclosed |
| US-5151505-A | Monoazo dyes containing hydroxypyrazole groups | CIBA-GEIGY CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| US-4980458-A | Mixed sodium, ammonium and/or calcium salt crystals of laked monoazo disulfonated pyrazolone pigments | CIBA-GEIGY CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0263074-A2 | Mixed crystals of laked azo dyes | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| EP-0241413-A2 | Amine salts of azo compounds | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |