SCHEMBL60535

SCHEMBL60535

Cc1cc(C)c(N(C)C)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 4/20 0.43
GAA P10253 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
ALDH1A1 P00352 4/20 0.36
TSHR P16473 3/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADRA2A P08913 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28184328 0.97 RAPGEF4 (0.41) RAPGEF4GAAMEN1KMT2APOLB
Hydrochloric Acid SCHEMBL3680590 0.97 RAPGEF4 (0.41) RAPGEF4GAAMEN1KMT2APOLB
Hydrochloric Acid SCHEMBL10934480 0.94 RAPGEF4 (0.39) RAPGEF4GAAMEN1KMT2APOLB
Hydrochloric Acid SCHEMBL10934482 0.91 RAPGEF4 (0.38) RAPGEF4GAAMEN1KMT2APOLB
Boric Acid SCHEMBL29088260 0.89 RAPGEF4 (0.36) RAPGEF4GAAMEN1KMT2APOLB
Boric Acid SCHEMBL30513397 0.89 RAPGEF4 (0.36) RAPGEF4GAAMEN1KMT2APOLB
SCHEMBL18780224 0.81 RAPGEF4 (0.35) RAPGEF4GAAALDH1A1KDM4ELMNA
SCHEMBL27650373 0.81 RAPGEF4 (0.35) RAPGEF4GAAALDH1A1KDM4ELMNA
SCHEMBL18966862 0.81 RAPGEF4 (0.35) RAPGEF4GAAALDH1A1KDM4ELMNA
SCHEMBL11433063 0.81 SELL (0.48) RAPGEF4GAAKMT2APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1984 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250162992-A1 METHOD FOR PRODUCING AMIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-22 US claimed
CN-114867758-B Metallocene and method thereof 埃克森美孚化学专利公司 2025-04-08 CN claimed
CN-118184915-A Propylene and alpha-olefin multi-block copolymer elastomer material, and preparation method and application thereof 天津大学 2024-06-14 CN claimed
CN-114478889-B Ethylene polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-06-04 CN claimed
CN-114479227-B Polyolefin composition and preparation method and application thereof 中国石油化工股份有限公司 2024-06-04 CN claimed
CN-117925054-A Water-based epoxy antirust paint and preparation method thereof 江门市制漆厂有限公司 2024-04-26 CN claimed
CN-113614123-B Transition metal bis (phenoxide) complexes and their use as olefin polymerization catalysts 埃克森美孚化学专利公司 2024-01-23 CN claimed
CN-116917354-A Polyethylene for preparing fiber and preparation method thereof 株式会社LG化学 2023-10-20 CN claimed
US-11760814-B2 1,5 diazabicyclooctane ligand systems and methods therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-19 US claimed
CN-116490528-A Polymer compositions containing cyclics obtained using transition metal bis (phenoxide) catalyst complexes and process for their preparation 埃克森美孚化学专利公司 2023-07-25 CN claimed
EP-0738285-A4 CATIONIC POLYMERIZATION SPECTRA GROUP LTD INC (US) 1996-12-18 EP claimed
EP-0738285-A1 CATIONIC POLYMERIZATION SPECTRA GROUP LIMITED INC (US) 1996-10-23 EP claimed
WO-1995014716-A1 CATIONIC POLYMERIZATION SPECTRA GROUP LIMITED, INC. (US) 1995-06-01 WO claimed
US-5420356-A Process for producing cyclobutanones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-30 US claimed
WO-1991016360-A1 COMPOSITIONS CONTAINING ORGANIC-SOLUBLE XANTHENE DYE PHOTOINITIATORS OLIN CORPORATION (US) 1991-10-31 WO claimed
US-4940645-A Imaging material employing photosensitive microcapsules containing tertiary amines as coinitiators THE MEAD CORPORATION (US) 1990-07-10 US claimed
EP-0043716-B1 PHOTOSENSITIVE COMPOSITION AND PATTERN FORMING PROCESS USING SAME Hitachi, Ltd. (JP) 1985-04-10 EP claimed
US-4409313-A Powder deposition to form pattern on light imaged photosensitive diazonium salt coating having salt of aromatic amine HITACHI, LTD. (JP) 1983-10-11 US claimed
US-4377630-A COMPRISING AN AROMATIC DIAZONIUM SALT AND N,N-DIALKYL ANILINE SALT HITACHI, LTD. (JP) 1983-03-22 US claimed
EP-0043716-A2 Photosensitive composition and pattern forming process using same Hitachi, Ltd. (JP) 1982-01-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760814-B2 1,5 diazabicyclooctane ligand systems and methods therewith ODC1, DDT, OXGR1 RAPGEF4 543/4885GAA 3256/4885MEN1 1775/4885
US-20250162992-A1 METHOD FOR PRODUCING AMIDE COMPOUND NAAA, NCAPH, NCAPD2 RAPGEF4 2619/4885GAA 2190/4885MEN1 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.