Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.42 |
| ▸ | CASP6 | P55212 | 3/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492525 | 0.81 | CASP3 (0.41) | CASP3CASP6CASP8L3MBTL1POLB | |
| SCHEMBL5492413 | 0.76 | CASP3 (0.35) | CASP3CASP6CASP8 | |
| SCHEMBL6054137 | 0.72 | CASP3 (0.46) | CASP3CASP6CASP8L3MBTL1CASP1 | |
| SCHEMBL7111386 | 0.69 | ALDH1A1 (0.38) | CASP3CASP6CASP8ALDH1A1CASP1 | |
| SCHEMBL14521758 | 0.62 | L3MBTL1 (1.00) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9544162 | 0.61 | L3MBTL1 (0.66) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5006073 | 0.61 | L3MBTL1 (0.61) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5495941 | 0.60 | CASP3 (0.34) | CASP3CASP6CASP8ALDH1A1 | |
| SCHEMBL5804308 | 0.59 | L3MBTL1 (0.67) | L3MBTL1KMT2AALDH1A1MAOBLMNA | |
| SCHEMBL2095643 | 0.59 | L3MBTL1 (0.67) | L3MBTL1POLBALDH1A1MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053056-B2 | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS, INC. (US) | 2006-05-30 | — | — | US | claimed |