Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785092 | 0.87 | CSF1R (0.63) | ALDH1A1CSF1RMEN1KMT2AKDM4E | |
| SCHEMBL17077982 | 0.87 | CSF1R (0.60) | ALDH1A1CSF1RMEN1KMT2APRNP | |
| SCHEMBL8786172 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6055809 | 0.82 | LMNA (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9149221 | 0.80 | ALOX5 (0.53) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL3640653 | 0.77 | KDM4E (0.49) | ALDH1A1MEN1KMT2APRNPKDM4E | |
| SCHEMBL9153220 | 0.76 | ALOX5 (0.58) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL31533269 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6055886 | 0.76 | KDM4E (0.47) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL3079215 | 0.74 | ERAP1 (0.63) | ALDH1A1KMT2AKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060035865-A1 | Lipid-rich plaque regressing agents | TERASHITA ZEN-ICHI | 2006-02-16 | — | — | US | disclosed |
| US-6974806-B2 | Lipid-rich plaque inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-13 | — | — | US | disclosed |
| US-20030232809-A1 | Lipid-rich plaque inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-18 | — | — | US | disclosed |
| EP-1302470-A1 | LIPID-RICH PLAQUE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035865-A1 | Lipid-rich plaque regressing agents | NR1H2, NR1H3, LDLR | ALDH1A1 3900/4885CSF1R 101/4885MEN1 4118/4885 |
| US-20030232809-A1 | Lipid-rich plaque inhibitors | LDLR, NR1H2, NR1H3 | ALDH1A1 2807/4885CSF1R 92/4885MEN1 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.