Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 19/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 17/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 17/20 | 0.43 |
| ▸ | GABRP | O00591 | 15/20 | 0.43 |
| ▸ | GABRD | O14764 | 15/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 15/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 15/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 15/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 15/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 15/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 15/20 | 0.43 |
| ▸ | GABRE | P78334 | 15/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 15/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 15/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 15/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 15/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055739 | 0.91 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055913 | 0.89 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055825 | 0.88 | GABRP (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055782 | 0.86 | GABRP (0.42) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7819222 | 0.85 | GABRP (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7825819 | 0.85 | GABRP (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7829679 | 0.84 | GABRP (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL4202646 | 0.84 | GABRP (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055897 | 0.84 | GABRP (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055895 | 0.83 | GABRP (0.42) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236938-A | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles | RHONE-POULENC INC. (US) | 1993-08-17 | — | — | US | claimed |
| EP-0511845-A1 | Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1992-11-04 | — | — | EP | claimed |
| US-20060105969-A1 | Anthelmintic compositions | BRUCE CHRISTOPHER I | 2006-05-18 | — | — | US | disclosed |
| EP-0511845-B1 | Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles | AVENTIS CROPSCIENCE SA (FR) | 2001-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105969-A1 | Anthelmintic compositions | TUBB, TUBA3C, CYP51A1 | GABRB3 2417/4885GABRA2 3701/4885GABRB2 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.