Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11853033 | 0.90 | GAA (0.68) | GAAHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL31000980 | 0.90 | GAA (0.68) | GAAHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1516456 | 0.84 | TSHR (0.58) | GAAHTTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8429342 | 0.83 | GAA (0.50) | GAAHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7146564 | 0.83 | GAA (0.54) | GAAHTTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL28132945 | 0.82 | TSHR (0.56) | GAAHTTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL29121431 | 0.82 | TSHR (0.56) | GAAHTTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL28881125 | 0.82 | TSHR (0.56) | GAAHTTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL29911012 | 0.81 | L3MBTL1 (0.59) | GAAHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL14060214 | 0.81 | CA2 (0.57) | GAAHTTSMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6995279-B2 | Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes | CHISSO CORPORATION (JP) | 2006-02-07 | — | — | US | disclosed |
| US-20040127731-A1 | Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes | CHISSO CORPORATION (JP) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127731-A1 | Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes | MLX, ZYX, YBX1 | GAA 2200/4885HTT 4727/4885SMN1; SMN2 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.