SCHEMBL6056974

SCHEMBL6056974

c1ccc(CCN2CC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.83
SIGMAR1 Q99720 3/20 0.79
HTR1A P08908 1/20 0.77
DRD2 P14416 1/20 0.77
ACHE P22303 1/20 0.68
CCR3 P51677 1/20 0.66
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
KCNH2 Q12809 1/20 0.65
MAPT P10636 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13150782 1.00 SLC6A3 (0.83) SLC6A3SIGMAR1HTR1ADRD2ACHE
SCHEMBL7264546 1.00 SLC6A3 (0.83) SLC6A3SIGMAR1HTR1ADRD2ACHE
SCHEMBL14407778 1.00 SLC6A3 (0.83) SLC6A3SIGMAR1HTR1ADRD2ACHE
SCHEMBL10685564 0.93 SIGMAR1 (0.80) SLC6A3SIGMAR1HTR1ADRD2CCR3
SCHEMBL422176 0.91 SIGMAR1 (0.76) SLC6A3SIGMAR1HTR1ADRD2ACHE
Hydrochloric Acid SCHEMBL9222207 0.91 SLC6A3 (0.84) SLC6A3SIGMAR1HTR1ADRD2ACHE
Hydrochloric Acid SCHEMBL11076651 0.91 SIGMAR1 (0.77) SLC6A3SIGMAR1HTR1ADRD2CCR3
SCHEMBL9597186 0.91 SLC6A3 (0.91) SLC6A3SIGMAR1HTR1ADRD2ACHE
SCHEMBL2876271 0.91 SLC6A3 (1.00) SLC6A3SIGMAR1HTR1ADRD2ACHE
SCHEMBL9410829 0.89 SLC6A3 (0.68) SLC6A3SIGMAR1HTR1ADRD2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4190471-A Pyrotechnic disseminating formulations THE DOW CHEMICAL COMPANY (US) 1980-02-26 US claimed
US-3974004-A Extension of pot life of HTPB composite propellants by phosphine oxides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-08-10 US claimed
US-3953257-A Method for preparing small particle size coated ammonium perchlorate THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-04-27 US claimed
US-11179957-B2 Primer for inkjet and method for manufacturing a printed material TOYOINK AMERICA, LLC (US) 2021-11-23 US disclosed
US-20210016589-A1 PRIMER FOR INKJET AND METHOD FOR MANUFACTURING A PRINTED MATERIAL TOYOINK AMERICA, LLC. (US) 2021-01-21 US disclosed
EP-1375593-B1 Resin composition NIPPON CATALYTIC CHEM IND (JP) 2006-12-27 EP disclosed
EP-1158031-B1 Aqueous fast-drying resin composition and its production process and use NIPPON CATALYTIC CHEM IND (JP) 2004-12-15 EP disclosed
EP-0846731-B1 Curable resin composition, adhesive and laminate thereof NIPPON CATALYTIC CHEM IND (JP) 2004-09-29 EP disclosed
US-6730746-B2 CARBOXYL-CONTAINING POLYMER HAVING PRIMARY AND/OR SECONDARY AMINO GROUPS, AND A POLYVALENT METAL COMPOUND; AN ACRYLIC ACID COPOLYMER MODIFIED WITH ETHYLENEIMINE FOR EXAMPLE AND AMMONIUM ZINC CARBOXYLATE; FILM FORMING NIPPON SHOKUBAI CO., LTD. (JP) 2004-05-04 US disclosed
JP-2004067611-A METHOD FOR PRODUCING AZIRIDINE DERIVATIVE TORAY IND INC 2004-03-04 JP disclosed
EP-1375593-A1 Resin composition Nippon Shokubai Co., Ltd. (JP) 2004-01-02 EP disclosed
US-4019933-A HYDROXY TERMINATED POLYBUTADIENE, AMMONIUM PERCHLORATE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1977-04-26 US disclosed
US-4018849-A Polyurethane polyol compositions modified with an alkylenimine PPG INDUSTRIES, INC. (US) 1977-04-19 US disclosed
US-3996193-A POLYALKYLENEPOLYAMINES, DIOLEFIN RUBBER THE DOW CHEMICAL COMPANY (US) 1976-12-07 US disclosed
US-3995059-A CHOLESTEROL LOWERING AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-11-30 US disclosed
US-3974004-A Extension of pot life of HTPB composite propellants by phosphine oxides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-08-10 US disclosed
US-3966667-A Preparation of non-aqueous thermosetting acrylic polymer dispersions PPG INDUSTRIES, INC. (US) 1976-06-29 US disclosed
US-3959228-A Low carboxyl high molecular weight polyesters THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-05-25 US disclosed
US-3953257-A Method for preparing small particle size coated ammonium perchlorate THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-04-27 US disclosed
US-3935269-A Copolymers of N-substituted aziridines and epoxides episulfides THE DOW CHEMICAL COMPANY (US) 1976-01-27 US disclosed