Acetic Acid

Acetic Acid

SCHEMBL605702

CC(=O)O.CCOCC(O)CC

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.35
HSD17B10 Q99714 2/20 0.33
USP2 O75604 2/20 0.33
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
THRB P10828 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.31
LPAR5 Q9H1C0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12011139 0.88
SCHEMBL13838795 0.88
SCHEMBL684370 0.88
Acetic Acid SCHEMBL7773024 0.84 USP2 (0.47) TSHRALDH1A1KDM4EHSD17B10USP2
SCHEMBL14667423 0.83 KDM4E (0.44) TSHRALDH1A1KDM4EHSD17B10USP2
Acetic Acid SCHEMBL27436234 0.81 USP2 (0.40) TSHRALDH1A1KDM4EHSD17B10USP2
SCHEMBL7481671 0.80 KDM4E (0.39) TSHRKDM4EHSD17B10USP2MEN1
Acetic Acid SCHEMBL4212999 0.79 GPR84 (0.44) TSHRALDH1A1KDM4EUSP2ALOX15
Acetic Acid SCHEMBL60591 0.79 HSD17B10 (0.50) TSHRALDH1A1HSD17B10LMNATHRB
SCHEMBL13173440 0.79 HSD17B10 (0.44) TSHRALDH1A1KDM4EHSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170165949-A1 HEAT SHIELDING MATERIAL, HEAT SHIELDING COMPOSITION AND HEAT SHIELDING STRUCTURE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-15 US claimed
US-20170167807-A1 HEAT SHIELDING MATERIAL, HEAT SHIELDING COMPOSITION AND HEAT SHIELDING STRUCTURE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-15 US claimed
US-8168689-B2 High optical contrast pigment and colorful photosensitive composition employing the same and fabrication method thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-05-01 US claimed
US-20090085016-A1 HIGH OPTICAL CONTRAST PIGMENT AND COLORFUL PHOTOSENSITIVE COMPOSITION EMPLOYING THE SAME AND FABRICATION METHOD THEREOF INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-04-02 US claimed
CN-109912908-B Substrate composition and substrate prepared therefrom 财团法人工业技术研究院 2021-05-18 CN disclosed
US-10640637-B2 Substrate composition and substrate prepared therefrom INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2020-05-05 US disclosed
CN-108239501-B Adhesive composition and composite base material containing same 财团法人工业技术研究院 2020-03-31 CN disclosed
US-20190177527-A1 SUBSTRATE COMPOSITION AND SUBSTRATE PREPARED THEREFROM INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2019-06-13 US disclosed
US-20180179424-A1 ADHESIVE COMPOSITION AND COMPOSITE SUBSTRATE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-06-28 US disclosed
US-20170165949-A1 HEAT SHIELDING MATERIAL, HEAT SHIELDING COMPOSITION AND HEAT SHIELDING STRUCTURE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-15 US disclosed
US-20170167807-A1 HEAT SHIELDING MATERIAL, HEAT SHIELDING COMPOSITION AND HEAT SHIELDING STRUCTURE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-15 US disclosed
US-9434652-B2 Infrared absorption material, method for fabricating the same, and thermal isolation structure employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-09-06 US disclosed
US-8969458-B2 Transparent heat shielding composition INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-03-03 US disclosed
US-20150030802-A1 INFRARED ABSORPTION MATERIAL, METHOD FOR FABRICATING THE SAME, AND THERMAL ISOLATION STRUCTURE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-01-29 US disclosed
US-20140187701-A1 TRANSPARENT HEAT SHIELDING COMPOSITION INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-07-03 US disclosed
US-8168689-B2 High optical contrast pigment and colorful photosensitive composition employing the same and fabrication method thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-05-01 US disclosed
US-20120038862-A1 LIQUID CRYSTAL DISPLAY PANEL AND COLOR FILTER SUBSTRATE AU OPTRONICS CORPORATION (TW) 2012-02-16 US disclosed
US-20090266788-A1 METHOD FOR FABRICATING CONDUCTIVE PATTERN ON FLEXIBLE SUBSTRATE AND PROTECTIVE INK USED THEREIN INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-10-29 US disclosed
US-20090085016-A1 HIGH OPTICAL CONTRAST PIGMENT AND COLORFUL PHOTOSENSITIVE COMPOSITION EMPLOYING THE SAME AND FABRICATION METHOD THEREOF INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-04-02 US disclosed
US-6255032-B1 Chemically amplified color resist composition INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-07-03 US disclosed