Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078845 | 0.91 | PKM (0.44) | MAPK1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL2996635 | 0.81 | TSHR (0.53) | MAPK1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL5239795 | 0.80 | MAPK8 (0.51) | MAPK1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL6059022 | 0.75 | ALDH1A1 (0.43) | MAPK1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL5077043 | 0.75 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDGLAPKM | |
| SCHEMBL7059436 | 0.75 | ALDH1A1 (0.59) | MAPK1KDM4EALDH1A1PKMHSD17B10 | |
| SCHEMBL28407232 | 0.74 | ALDH1A1 (0.50) | MAPK1KDM4EALDH1A1GAAPKM | |
| SCHEMBL1973549 | 0.74 | KDM4E (0.57) | MAPK1KDM4EALDH1A1GAAHPGD | |
| Ethane SCHEMBL28902205 | 0.74 | ALDH1A1 (0.57) | MAPK1KDM4EALDH1A1PKMHSD17B10 | |
| SCHEMBL698811 | 0.73 | ALDH1A1 (0.51) | MAPK1KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678218-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005047351-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2005-05-26 | — | — | WO | disclosed |