Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NCK1 | P16333 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16541640 | 0.86 | NPC1 (0.49) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14084759 | 0.85 | CYP1A2 (0.53) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21622433 | 0.85 | PDE10A (0.50) | ALDH1A1CYP1A2NCK1BACE1PARP1 | |
| SCHEMBL9814928 | 0.80 | FAAH (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9334190 | 0.80 | PDE10A (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18562139 | 0.80 | CYP1A2 (0.40) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4572536 | 0.80 | CYP1A2 (0.65) | ALDH1A1CYP1A2KDM4ENCK1BACE1 | |
| SCHEMBL9814937 | 0.77 | PDGFRB (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL18561916 | 0.77 | PDE10A (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2PARP1 | |
| SCHEMBL14084762 | 0.77 | NPC1 (0.41) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089975-B1 | IMPROVED METHOD FOR PRODUCING SUBSTITUTED PYRIDINE-CARBOXYLIC ACIDS | DSM FINE CHEM AUSTRIA GMBH (AT) | 2004-04-28 | — | — | EP | claimed |
| EP-1089975-A1 | IMPROVED METHOD FOR PRODUCING SUBSTITUTED PYRIDINE-CARBOXYLIC ACIDS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2001-04-11 | — | — | EP | claimed |
| WO-1999067217-A2 | METHOD FOR PRODUCING SUBSTITUTED PYRIDINE-CARBOXYLIC ACIDS | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 1999-12-29 | — | — | WO | claimed |
| WO-2020198435-A1 | SMALL MOLECULE DEGRADERS OF STAT3 | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-10-01 | — | — | WO | disclosed |
| EP-2861601-B1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2018-02-07 | — | — | EP | disclosed |
| US-8470829-B2 | Imidazolidine derivative and use thereof | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20110306615-A1 | NOVEL IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-12-15 | — | — | US | disclosed |
| US-7384552-B2 | Proton-conducting membrane and the use thereof | BASF FUEL CELL GMBH (DE) | 2008-06-10 | — | — | US | disclosed |
| US-7235320-B2 | Proton-conducting membrane and use thereof | PEMEAS GMBH (DE) | 2007-06-26 | — | — | US | disclosed |
| EP-1366008-B1 | METHOD FOR PRODUCING MONOCARBONYL COMPOUNDS OR BISCARBONYL COMPOUNDS OR HYDROXYL COMPOUNDS | DSM FINE CHEM AUSTRIA GMBH (AT) | 2006-11-22 | — | — | EP | disclosed |
| EP-1089975-B1 | IMPROVED METHOD FOR PRODUCING SUBSTITUTED PYRIDINE-CARBOXYLIC ACIDS | DSM FINE CHEM AUSTRIA GMBH (AT) | 2004-04-28 | — | — | EP | disclosed |
| EP-1366008-A2 | METHOD FOR PRODUCING MONOCARBONYL COMPOUNDS OR BISCARBONYL COMPOUNDS OR HYDROXYL COMPOUNDS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002072518-A2 | METHOD FOR PRODUCING MONOCARBONYL COMPOUNDS OR BISCARBONYL COMPOUNDS OR HYDROXYL COMPOUNDS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-09-19 | — | — | WO | disclosed |
| EP-1089975-A1 | IMPROVED METHOD FOR PRODUCING SUBSTITUTED PYRIDINE-CARBOXYLIC ACIDS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067217-A2 | METHOD FOR PRODUCING SUBSTITUTED PYRIDINE-CARBOXYLIC ACIDS | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 1999-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306615-A1 | NOVEL IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | CBR1, NR0B1, CNKSR1 | ALDH1A1 989/4885CYP1A2 1005/4885NPC1 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.