Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.54 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094447 | 0.87 | HPGDS (0.56) | PDGFRBPDGFRAALDH1A1EGFRPDE10A | |
| SCHEMBL20193578 | 0.87 | ALDH1A1 (0.51) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL11996262 | 0.85 | PDGFRB (0.54) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL8813587 | 0.85 | CYP11B1 (0.55) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL8882652 | 0.85 | ALDH1A1 (0.57) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| Hydrochloric Acid SCHEMBL8882873 | 0.84 | PDGFRB (0.52) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| Ethane SCHEMBL27947703 | 0.84 | ALDH1A1 (0.56) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL7028923 | 0.82 | ALDH1A1 (0.70) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL16541640 | 0.82 | NPC1 (0.49) | PDGFRBPDGFRAALDH1A1HPGDPDE10A | |
| SCHEMBL31735898 | 0.80 | PTGS1 (0.66) | PDGFRBPDGFRAALDH1A1HPGDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323730-A1 | SUBSTITUTED ACETYL-COA CARBOXYLASE INHIBITORS | PFIZER (US) | 2014-10-30 | — | — | US | disclosed |
| EP-0247277-B1 | PROCESS FOR THE PREPARATION OF 5-ALKYLQUINOLINIC ACIDS AND MEANS FOR CARRYING OUT THIS PROCESS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0247277-A2 | Process for the preparation of 5-alkylquinolinic acids and means for carrying out this process | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1987-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323730-A1 | SUBSTITUTED ACETYL-COA CARBOXYLASE INHIBITORS | ACACA, ACACB, ACAT1 | PDGFRB 3234/4885PDGFRA 3061/4885ALDH1A1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.