SCHEMBL6058486

SCHEMBL6058486

CO[SiH](OC)C(CC(C)C)CC(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9412786 0.89
SCHEMBL7159375 0.81
SCHEMBL8469955 0.79 DNM1 (0.34)
SCHEMBL8852351 0.77 ALDH1A1 (0.32) ALDH1A1TSHRMAPK1
SCHEMBL1608598 0.75 TSHR (0.33) TSHR
SCHEMBL28809634 0.73 CA12 (0.31) ALDH1A1
SCHEMBL1070706 0.72 TSHR (0.41) ALDH1A1TSHRMAPK1
SCHEMBL525614 0.72
SCHEMBL9283131 0.69
SCHEMBL5833505 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104955851-A Heterogeneous Ziegler-natta catalyst system and a process for olefin polymerization using the same RELIANCE IND LTD 2015-09-30 CN disclosed
US-20060116280-A1 Catalysts for polymerizing olefins and process for producing olefin polymer IDEMITSU KOSAN CO., LTD. (JP) 2006-06-01 US disclosed
CN-1735632-A catalyst for olefin polymerization and process for producing olefin polymer IDEMITSU PETROCHEMICAL CO (JP) 2006-02-15 CN disclosed
EP-1586589-A1 CATALYSTS FOR POLYMERIZING OLEFINS AND PROCESS FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO., LTD. (JP) 2005-10-19 EP disclosed