SCHEMBL1070706

SCHEMBL1070706

CO[SiH](OC)C(N)CC(C)C

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
ANPEP P15144 5/20 0.35
ERAP1 Q9NZ08 2/20 0.35
ERAP2 Q6P179 1/20 0.35
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC7A5 Q01650 1/20 0.32
LAP3 P28838 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2830814 0.75 TSHR (0.38) TSHRALDH1A1MAPK1ANPEPERAP1
SCHEMBL1070260 0.72
SCHEMBL8852351 0.72 ALDH1A1 (0.32) TSHRALDH1A1MAPK1
SCHEMBL6058486 0.72 ALDH1A1 (0.32) TSHRALDH1A1MAPK1
SCHEMBL17650 0.70 ALDH1A1 (0.33) TSHRALDH1A1MAPK1
SCHEMBL525614 0.68
SCHEMBL142524 0.68
SCHEMBL9412786 0.68
SCHEMBL2341654 0.67
Methylamine SCHEMBL28486503 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3877438-A1 METHOD FOR PRODUCING SILANE-MODIFIED POLYMERS merz+benteli ag (CH) 2021-09-15 EP claimed
EP-2828313-A2 TWO PART SIZING COMPOSITION FOR COATING GLASS FIBRES AND COMPOSITE REINFORCED WITH SUCH GLASS FIBRES 3B-Fibreglass SPRL (BE) 2015-01-28 EP claimed
EP-2768786-A2 SIZING COMPOSITION FOR GLASS FIBRES 3B-Fibreglass SPRL (BE) 2014-08-27 EP claimed
WO-2013139708-A2 TWO PART SIZING COMPOSITION FOR COATING GLASS FIBRES AND COMPOSITE REINFORCED WITH SUCH GLASS FIBRES 3B FIBREGLASS SPRL (BE) 2013-09-26 WO claimed
WO-2013110515-A1 POLYAMIDE BASED SIZING COMPOSITION FOR GLASS FIBRES 3B-FIBREGLASS SPRL (BE) 2013-08-01 WO claimed
WO-2013057163-A2 SIZING COMPOSITION FOR GLASS FIBRES 3B FIBREGLASS SPRL (BE) 2013-04-25 WO claimed
EP-2147041-A2 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL Momentive Performance Materials Inc. (US) 2010-01-27 EP claimed
WO-2008133916-A2 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-11-06 WO claimed
US-20080268162-A1 Method of applying an anti-corrosion and/or adhesion promoting coating to a metal and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-30 US claimed
WO-2025045754-A1 POLYAMIDE MOULDING COMPOUND FOR PRODUCING COMPONENTS WITH A HIGH WELD LINE STRENGTH EMS-CHEMIE AG (CH) 2025-03-06 WO disclosed
US-11655404-B2 Sealant composition DOW SILICONES CORPORATION (US) 2023-05-23 US disclosed
US-20230094559-A1 SEALANT COMPOSITION DOW SILICONES CORPORATION 2023-03-30 US disclosed
EP-2147041-B1 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MAT INC (US) 2017-08-23 EP disclosed
EP-2152720-B1 HYDROXYL-FUNCTIONAL CARBAMOYL ORGANOSILICON COMPOUNDS OF LOW VOC AND HAP GENERATING POTENTIAL, ANTI-CORROSION AND/OR ADHESION PROMOTING COATING COMPOSITIONS CONTAINING SAME, ENVIRONMENTALLY BENIGN METHOD OF COATING METAL THEREWITH AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MAT INC (US) 2015-07-29 EP disclosed
WO-2008133907-A1 HYDROXYL-FUNCTIONAL CARBAMOYL ORGANOSILICON COMPOUNDS OF LOW VOC AND HAP GENERATING POTENTIAL, ANTI-CORROSION AND/OR ADHESION PROMOTING COATING COMPOSITIONS CONTAINING SAME, ENVIRONMENTALLY BENIGN METHOD OF COATING METAL THEREWITH AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-11-06 WO disclosed
WO-2008133916-A2 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-11-06 WO disclosed
US-20080268162-A1 Method of applying an anti-corrosion and/or adhesion promoting coating to a metal and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-30 US disclosed
US-20080268146-A1 Hydroxyl-functional carbamoyl organosilicon compounds of low VOC and HAP generating potential, anti-corrosion and/or adhesion promoting coating composition containing same, enviromenttally beign method of coating metal therewith and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-30 US disclosed
US-6121404-A PREPARED BY REACTING DIKETENE OR EQUIVALENT ACETOACETOXYLATING AGENT WITH AN ORGANOSILICON NUCLEOPHILE IN WHICH THE ORGANOSILICON NUCLEOPHILE IS A HYDROXYORGANOSILANE DOW CORNING CORPORATION (US) 2000-09-19 US disclosed
EP-0400785-A2 Ultraviolet curable phenyl and acrylamide group-containing silicone compositions DOW CORNING CORPORATION (US) 1990-12-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080268146-A1 Hydroxyl-functional carbamoyl organosilicon compounds of low VOC and HAP generating potential, anti-corrosion and/or adhesion promoting coating composition containing same, enviromenttally beign method of coating metal therewith and resulting coated metal HAAO, HAO2, COMT TSHR 4594/4885ALDH1A1 1227/4885MAPK1 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.