SCHEMBL6155680

SCHEMBL6155680

CC(C)(C)[Si](C)(C)Oc1cc(O[Si](C)(C)C(C)(C)C)cc(C(=O)O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.41
CA12 O43570 5/20 0.41
CA1 P00915 5/20 0.41
CA9 Q16790 5/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TPMT P51580 2/20 0.38
PREP P48147 3/20 0.37
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HIF1A Q16665 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
PKM P14618 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3296656 0.96 CA12 (0.41) PLA2G2ACA12CA1CA9MEN1
SCHEMBL25665190 0.93 RXRA (0.46) CA12CA1CA9TPMTCA2
SCHEMBL7558013 0.92 PLA2G2A (0.36) PLA2G2ACA12CA1CA9MEN1
SCHEMBL6654531 0.89 TPMT (0.48) PLA2G2ACA12CA1CA9TPMT
SCHEMBL6114920 0.85 CA12 (0.41) CA12CA1CA9MEN1KMT2A
SCHEMBL29831305 0.84 CA12 (0.40) CA12CA1CA9PREP
SCHEMBL18120875 0.83 CA12 (0.38) CA12CA1CA9PREP
SCHEMBL2989104 0.83 AKR1C3 (0.53) CA12CA1CA9KMT2ARXRA
SCHEMBL6625609 0.82 KDM4E (0.44) CA12CA1CA9PREPTSHR
SCHEMBL7558007 0.82 CA12 (0.39) CA12CA1CA9PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149930-B Cell sugar transport channel inhibitor 天津大学 2022-09-02 CN disclosed
CN-111808059-B Tumor diagnosis and treatment fluorescent probe targeting tumor Woberg effect 天津大学 2022-09-02 CN disclosed
US-10975307-B2 Liquid crystalline epoxy compound with terminal mesogen connected by flexible linkage and method for preparing the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2021-04-13 US disclosed
US-10975307-B2 Liquid crystalline epoxy compound with terminal mesogen connected by flexible linkage and method for preparing the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2021-04-13 US disclosed
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US disclosed
US-20180201835-A1 LIQUID CRYSTALLINE EPOXY COMPOUND WITH TERMINAL MESOGEN CONNECTED BY FLEXIBLE LINKAGE AND METHOD FOR PREPARING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-07-19 US disclosed
US-20180201835-A1 LIQUID CRYSTALLINE EPOXY COMPOUND WITH TERMINAL MESOGEN CONNECTED BY FLEXIBLE LINKAGE AND METHOD FOR PREPARING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-07-19 US disclosed
US-20180201835-A1 LIQUID CRYSTALLINE EPOXY COMPOUND WITH TERMINAL MESOGEN CONNECTED BY FLEXIBLE LINKAGE AND METHOD FOR PREPARING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-07-19 US disclosed
US-9896547-B2 Polymerization method and polymers formed therewith THE SCRIPPS RESEARCH INSTITUTE (US) 2018-02-20 US disclosed
EP-2925803-B1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH SCRIPPS RESEARCH INST (US) 2017-11-29 EP disclosed
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US disclosed
US-9447243-B2 Polymerization method and polymers formed therewith THE SCRIPPS RESEARCH INSTITUTE (US) 2016-09-20 US disclosed
US-20150315340-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH THE SCRIPPS RESEARCH INSTITUTE 2015-11-05 US disclosed
EP-2925803-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH The Scripps Research Institute (US) 2015-10-07 EP disclosed
WO-2014089078-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH THE SCRIPPS RESEARCH INSTITUTE (US) 2014-06-12 WO disclosed
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2012-03-01 US disclosed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP disclosed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 PLA2G2A 2551/4885CA12 1571/4885CA1 2621/4885
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 PLA2G2A 2551/4885CA12 1571/4885CA1 2621/4885
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 PLA2G2A 2551/4885CA12 1571/4885CA1 2621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.