SCHEMBL6059554

SCHEMBL6059554

CCCCCCOCCC(=O)C(O)Cc1ccc(O)c(OC)c1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.55
CYP2C9 P11712 5/20 0.55
CYP2C19 P33261 5/20 0.55
CYP2C8 P10632 4/20 0.55
CYP2B6 P20813 4/20 0.55
CYP1A2 P05177 4/20 0.55
CYP2D6 P10635 3/20 0.53
HTR1A P08908 3/20 0.53
CYP2A6 P11509 2/20 0.53
LTA4H P09960 2/20 0.53
CYP2E1 P05181 1/20 0.53
ALDH1A1 P00352 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
BLM P54132 1/20 0.53
PMP22 Q01453 1/20 0.53
TRPV1 Q8NER1 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060532 0.90 CYP3A4 (0.64) CYP3A4CYP2C9CYP2C19CYP2C8CYP2B6
SCHEMBL6059810 0.90 CYP3A4 (0.64) CYP3A4CYP2C9CYP2C19CYP2C8CYP2B6
SCHEMBL6059316 0.87 FOS (0.52) CYP3A4CYP2C9CYP2C19CYP2C8CYP2B6
SCHEMBL5702509 0.80 EPHX2 (0.60) CYP3A4CYP2C9CYP2C19CYP2C8CYP2B6
SCHEMBL5160966 0.79 CYP1A2 (0.80) CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6
SCHEMBL18454017 0.78 HTR1A (0.64) CYP3A4CYP2C9CYP2C19CYP2C8CYP2B6
Vanillyl Alcohol SCHEMBL117979 0.78 CYP1A2 (0.56) CYP3A4CYP2C9CYP2C19CYP2C8CYP2B6
Alcohol SCHEMBL579289 0.77 CYP1A2 (0.55) CYP3A4CYP2C9CYP2C19CYP2C8CYP2B6
Vanillyl Alcohol SCHEMBL3386819 0.77 CYP1A2 (0.55) CYP3A4CYP2C9CYP2C19CYP2C8CYP2B6
Vanillyl Alcohol SCHEMBL15272606 0.77 CYP1A2 (0.55) CYP3A4CYP2C9CYP2C19CYP2C8CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006125276-A1 PHENYLALKANOL COMPOUNDS ZINGOTX PTY LTD (AU) 2006-11-30 WO disclosed