Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | FOS | P01100 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060001 | 0.80 | FOS (0.61) | TRPV1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6060532 | 0.79 | CYP3A4 (0.64) | TRPV1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6059810 | 0.79 | CYP3A4 (0.64) | TRPV1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6059316 | 0.76 | FOS (0.52) | TRPV1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL19839958 | 0.76 | TRPV1 (0.55) | TRPV1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL27870957 | 0.75 | CYP3A4 (0.59) | TRPV1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL2454609 | 0.75 | KDM6B (0.66) | TRPV1CYP3A4TSHRPOLBBLM | |
| SCHEMBL31167480 | 0.75 | KDM6B (0.66) | TRPV1CYP3A4TSHRPOLBBLM | |
| SCHEMBL29426370 | 0.75 | KDM6B (0.66) | TRPV1CYP3A4TSHRPOLBBLM | |
| SCHEMBL6059554 | 0.74 | CYP3A4 (0.55) | TRPV1CYP3A4CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125276-A1 | PHENYLALKANOL COMPOUNDS | ZINGOTX PTY LTD (AU) | 2006-11-30 | — | — | WO | disclosed |