Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FOS | P01100 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30242334 | 0.90 | TSHR (0.58) | TSHRMEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL17179832 | 0.90 | TSHR (0.58) | TSHRMEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL17655545 | 0.88 | CYP3A4 (0.60) | TRPV1TSHRMEN1CYP1A2POLB | |
| SCHEMBL19839967 | 0.83 | ALOX15 (0.49) | TRPV1TSHRALDH1A1GAANFKB1 | |
| SCHEMBL21046217 | 0.83 | ALOX15 (0.49) | TRPV1TSHRALDH1A1GAANFKB1 | |
| SCHEMBL19839960 | 0.83 | ALOX15 (0.49) | TRPV1TSHRALDH1A1GAANFKB1 | |
| SCHEMBL31432604 | 0.80 | TSHR (0.61) | TSHRMEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL17179836 | 0.80 | TSHR (0.61) | TSHRMEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL25061851 | 0.79 | TSHR (0.60) | TSHRCYP3A4ALDH1A1GAANFKB1 | |
| SCHEMBL17179861 | 0.79 | ALDH1A1 (0.60) | TRPV1TSHRCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-109803948-B | Warming sensation compound | 高砂香料工业株式会社 | 2022-03-01 | — | — | CN | disclosed |
| US-11059771-B2 | Warming sensation compounds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2021-07-13 | — | — | US | disclosed |
| US-11034644-B2 | — | — | 2021-06-15 | — | — | US | disclosed |
| EP-3494104-A1 | WARMING SENSATION COMPOUNDS | Takasago International Corporation (JP) | 2019-06-12 | — | — | EP | disclosed |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-06-06 | — | — | US | disclosed |
| WO-2018027202-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (USA) (US) | 2018-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059771-B2 | Warming sensation compounds | TRPA1, TRPV1, TRPV4 | TRPV1 2/4885TSHR 3146/4885MEN1 2560/4885 |
| US-11034644-B2 | — | TRPA1, TRPV1, TRPV5 | TRPV1 2/4885TSHR 3981/4885MEN1 2867/4885 |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TRPA1, TRPV1, TRPV4 | TRPV1 2/4885TSHR 3146/4885MEN1 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.