SCHEMBL6060426

SCHEMBL6060426

CCCCCC1([Si](C)(C)C)C=CC(c2ccccc2)C=C1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.33
MMP9 P14780 4/20 0.33
KDM1A O60341 2/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 2/20 0.33
MMP13 P45452 2/20 0.33
SLC10A2 Q12908 4/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
GAA P10253 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
ALOX12 P18054 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9852458 0.80 OPRM1 (0.39) MMP2MMP9KDM1AMAOAMAOB
SCHEMBL9313274 0.78 KDM1A (0.35) MMP2MMP9KDM1AMAOAMAOB
SCHEMBL10527595 0.78 MMP2 (0.38) MMP2MMP9KDM1AMAOAMAOB
SCHEMBL8780389 0.77 MMP2 (0.40) MMP2MMP9KDM1AMAOAMAOB
SCHEMBL10346699 0.77 MMP2 (0.39) MMP2MMP9KDM1AMAOAMAOB
SCHEMBL407033 0.75 ALDH1A1 (0.34) MMP2MMP9KDM1AMAOAMAOB
SCHEMBL8634659 0.75 MMP2 (0.33) MMP2MMP9KDM1AMAOAMAOB
SCHEMBL4476022 0.74 MEN1 (0.36) MMP2MMP9KDM1AMAOAMAOB
SCHEMBL10440676 0.74 PPARG (0.39) MMP2MMP9MMP3MMP8MMP13
SCHEMBL8339744 0.74 MEN1 (0.36) MMP2MMP9KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1268588-A4 ETHYLENE-AROMATIC VINYL COMPOUND-VINYL NORBONENE TERPOLYMER SAMSUNG ATOFINA CO LTD (KR) 2006-03-29 EP disclosed
EP-1268588-A1 ETHYLENE-AROMATIC VINYL COMPOUND-VINYL NORBONENE TERPOLYMER Samsung General Chemicals Co., Ltd. (KR) 2003-01-02 EP disclosed
WO-2001046282-A1 ETHYLENE-AROMATIC VINYL COMPOUND-VINYL NORBONENE TERPOLYMER SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-06-28 WO disclosed