SCHEMBL6060593

SCHEMBL6060593

C[Si](C)(C)OC12CCCCC1C2

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23829718 0.76
SCHEMBL30507612 0.72
SCHEMBL7735455 0.66 HSD11B1 (0.35)
SCHEMBL12389949 0.66 HSD11B1 (0.35)
SCHEMBL7741566 0.64 HSD11B1 (0.34) LMNATSHR
SCHEMBL7739338 0.64 HSD11B1 (0.34) LMNATSHR
SCHEMBL7739168 0.64 HSD11B1 (0.34) LMNATSHR
SCHEMBL7738780 0.64 HSD11B1 (0.34) LMNATSHR
SCHEMBL12389943 0.64 HSD11B1 (0.34) LMNATSHR
SCHEMBL7733474 0.64 HSD11B1 (0.34) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1404687-B1 FLUOROUS TRIPHASE AND OTHER MULTIPHASE SYSTEMS UNIV PITTSBURGH (US) 2006-12-27 EP disclosed
US-6897331-B2 Fluorous triphase and other multiphase systems UNIVERSITY OF PITTSBURGH (US) 2005-05-24 US disclosed
EP-1404687-A4 FLUOROUS TRIPHASE AND OTHER MULTIPHASE SYSTEMS UNIV PITTSBURGH (US) 2004-10-27 EP disclosed
EP-1404687-A2 FLUOROUS TRIPHASE AND OTHER MULTIPHASE SYSTEMS UNIVERSITY OF PITTSBURGH (US) 2004-04-07 EP disclosed
US-20030125590-A1 Fluorous triphase and other multiphase systems NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-07-03 US disclosed
WO-2002100802-A2 FLUOROUS TRIPHASE AND OTHER MULTIPHASE SYSTEMS UNIVERSITY OF PITTSBURGH (US) 2002-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030125590-A1 Fluorous triphase and other multiphase systems DDT, CNDP2, PFAS LMNA 4409/4885TSHR 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.