Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602498 | 0.81 | KDM4E (0.46) | POLBLMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL1542688 | 0.81 | POLB (0.66) | POLBLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8824634 | 0.79 | POLB (0.55) | POLBLMNASMN1; SMN2L3MBTL1KCNN4 | |
| SCHEMBL9224803 | 0.77 | POLB (0.43) | POLBLMNASMN1; SMN2L3MBTL1KCNN4 | |
| SCHEMBL18307753 | 0.76 | FDPS (0.43) | POLBLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9228203 | 0.76 | POLB (0.42) | POLBLMNASMN1; SMN2L3MBTL1KCNN4 | |
| SCHEMBL28562456 | 0.75 | POLB (0.40) | POLBLMNAMAPTALDH1A1KDM4E | |
| SCHEMBL6060892 | 0.75 | FDPS (0.60) | POLBLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8831743 | 0.75 | POLB (0.38) | POLBLMNASMN1; SMN2L3MBTL1KCNN4 | |
| SCHEMBL31482560 | 0.75 | KCNA5 (0.47) | KCNN4KCNA5NPC1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482953-A4 | ALPHA-SUBSTITUTED HETEROARYLALKYL PHOSPHONATE DERIVATTIVES | ILEX PRODUCTS INC (US) | 2006-12-13 | — | — | EP | disclosed |
| US-20050124581-A1 | Alpha-substituted heteroarylalkyl phosphonate derivatives | PHAN HIEU T (CH) | 2005-06-09 | — | — | US | disclosed |
| EP-1482953-A1 | ALPHA-SUBSTITUTED HETEROARYLALKYL PHOSPHONATE DERIVATTIVES | Ilex Products, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003068240-A1 | ALPHA-SUBSTITUTED HETEROARYLALKYL PHOSPHONATE DERIVATTIVES | ILEX PRODUCTS, INC. (US) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124581-A1 | Alpha-substituted heteroarylalkyl phosphonate derivatives | APOB, APOL1, LDLR | POLB 1364/4885LMNA 276/4885SMN1; SMN2 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.