Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4992355 | 0.86 | PNMT (0.50) | ACP3SLC6A9PNMTEPHX1MEN1 | |
| SCHEMBL4993135 | 0.82 | HTR2A (0.55) | PPARGPPARAEPHX1CYP1A2CYP3A4 | |
| SCHEMBL4983450 | 0.82 | PPARA (0.45) | PPARGPPARAEPHX2PPARD | |
| SCHEMBL4989819 | 0.80 | PPARA (0.51) | PPARGPPARAEPHX2PPARD | |
| SCHEMBL4984304 | 0.77 | PNMT (0.51) | ACP3PNMTEPHX1MEN1ALDH1A1 | |
| SCHEMBL4990067 | 0.76 | PNMT (0.52) | ACP3SLC6A9PNMTEPHX1MEN1 | |
| SCHEMBL4985838 | 0.75 | CYP1A2 (0.55) | CYP1A2 | |
| SCHEMBL4993935 | 0.75 | GABBR2 (0.49) | CYP1A2POLBSMN1; SMN2HTR2A | |
| SCHEMBL4984410 | 0.75 | TAAR1 (0.49) | PPARGPPARAEPHX1MEN1KMT2A | |
| SCHEMBL4990933 | 0.74 | HTR2A (0.49) | PPARGPPARAEPHX2EPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667957-A2 | AMINO ACIDS WITH AFFINITY FOR THE ALPHA2DELTA-PROTEIN | Warner-Lambert Company LLC (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005030700-A2 | AMINO ACIDS WITH AFFINITY FOR THE ALPHA2DELTA-PROTEIN | WARNER-LAMBERT COMPANY LLC (US) | 2005-04-07 | — | — | WO | claimed |