Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | BAX | Q07812 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GLI1 | P08151 | 1/20 | 0.39 |
| ▸ | GLI2 | P10070 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061153 | 0.87 | ALDH1A1 (0.45) | TYRLTA4HPOLBALDH1A1LMNA | |
| SCHEMBL6062347 | 0.84 | LTA4H (0.48) | LTA4HNR1H2BAXPTGS1MCL1 | |
| SCHEMBL5209521 | 0.83 | LTA4H (0.50) | TYRLTA4HNR1H2BAXPOLB | |
| SCHEMBL6061193 | 0.80 | TYR (0.60) | TYRLTA4HNR1H2BAXPOLB | |
| SCHEMBL6061390 | 0.80 | LTA4H (0.50) | TYRLTA4HNR1H2BAXPOLB | |
| SCHEMBL12806640 | 0.79 | LTA4H (0.53) | LTA4HNR1H2BAXPOLBALDH1A1 | |
| SCHEMBL6062066 | 0.79 | TYR (0.59) | TYRLTA4HALDH1A1MAPT | |
| SCHEMBL6061474 | 0.78 | CYP3A4 (0.62) | TYRLTA4HALDH1A1MAPT | |
| SCHEMBL31545069 | 0.77 | TYR (0.76) | TYRMAPT | |
| SCHEMBL940625 | 0.77 | TYR (0.76) | TYRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053989-B1 | Hydroxydiphenyl ether compounds | CIBA SC HOLDING AG (CH) | 2007-07-25 | — | — | EP | disclosed |
| US-7105577-B2 | for finishing of undyed and dyed or printed fibre materials; treatment of skin, mucous membrane or hair, hard surfaces, oral care; detergent | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |