Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449929 | 0.87 | GABRA1 (0.53) | LTA4HNR1H2BAXPTGS1PPARG | |
| SCHEMBL6061834 | 0.84 | TYR (0.47) | LTA4HNR1H2BAXPTGS1MCL1 | |
| SCHEMBL12806640 | 0.81 | LTA4H (0.53) | LTA4HNR1H2BAXALDH1A1ALOX12 | |
| SCHEMBL13719038 | 0.81 | LTA4H (0.41) | LTA4HPTGS1PPARGPPARDPPARA | |
| SCHEMBL17965863 | 0.80 | GAA (0.56) | GABRA1GABRB2ALDH1A1 | |
| SCHEMBL13719403 | 0.79 | TSHR (0.48) | LTA4HPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL5209521 | 0.79 | LTA4H (0.50) | LTA4HNR1H2BAXMAPTCAMK2A | |
| SCHEMBL1581538 | 0.78 | GABRA1 (0.61) | PPARGPPARDPPARAGABRA1GABRB2 | |
| SCHEMBL10269372 | 0.77 | LTA4H (0.44) | LTA4HPTGS1PPARGPPARDPPARA | |
| SCHEMBL7445377 | 0.77 | MAOB (0.44) | LTA4HPTGS1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002078-A1 | COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS | L'OREAL (FR) | 2003-01-09 | — | — | WO | claimed |
| WO-2003002080-A1 | COMPOSITIONS CONTAINING A DERIVATIVE OF HYDROXYDIPHENYL ETHER INHIBITING THE DEVELOPMENT OF BODY ODOURS | L'OREAL (FR) | 2003-01-09 | — | — | WO | claimed |
| WO-2003002081-A1 | COMPOSITION COMPRISING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING THE DEVELOPMENT OF BODY ODOURS | L'OREAL (FR) | 2003-01-09 | — | — | WO | claimed |
| WO-2003002072-A1 | COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS | L'ORÉAL (FR) | 2003-01-09 | — | — | WO | claimed |
| WO-2003002079-A1 | COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS | L'OREAL (FR) | 2003-01-09 | — | — | WO | claimed |
| US-20120328541-A1 | Anti-radical agents | BASCHONG WERNER (CH) | 2012-12-27 | — | — | US | disclosed |
| US-20120328541-A1 | Anti-radical agents | BASCHONG WERNER (CH) | 2012-12-27 | — | — | US | disclosed |
| EP-1827406-B1 | ANTI-RADICAL AGENTS | BASF SE (DE) | 2010-07-28 | — | — | EP | disclosed |
| US-20080305055-A1 | Anti-Radical Agents | CIBA CORPORATION | 2008-12-11 | — | — | US | disclosed |
| US-20080305055-A1 | Anti-Radical Agents | CIBA CORPORATION | 2008-12-11 | — | — | US | disclosed |
| EP-1053989-B1 | Hydroxydiphenyl ether compounds | CIBA SC HOLDING AG (CH) | 2007-07-25 | — | — | EP | disclosed |
| US-7105577-B2 | for finishing of undyed and dyed or printed fibre materials; treatment of skin, mucous membrane or hair, hard surfaces, oral care; detergent | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |
| US-20050203179-A1 | Especially suitable for inhibiting the development of body odour in men | CIBA SPECIALTY CHEMICALS CORP. | 2005-09-15 | — | — | US | disclosed |
| EP-1494640-A1 | USE OF HYDROXYDIPHENYL ETHER DERIVATIVES AS ARYLSULFATASE- INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS | Ciba SC Holding AG (CH) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003086338-A1 | USE OF HYDROXYDIPHENYL ETHER DERIVATIVES AS ARYLSULFATASE- INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-10-23 | — | — | WO | disclosed |
| WO-2003002081-A1 | COMPOSITION COMPRISING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING THE DEVELOPMENT OF BODY ODOURS | L'OREAL (FR) | 2003-01-09 | — | — | WO | disclosed |
| WO-2003002078-A1 | COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS | L'OREAL (FR) | 2003-01-09 | — | — | WO | disclosed |
| WO-2003002080-A1 | COMPOSITIONS CONTAINING A DERIVATIVE OF HYDROXYDIPHENYL ETHER INHIBITING THE DEVELOPMENT OF BODY ODOURS | L'OREAL (FR) | 2003-01-09 | — | — | WO | disclosed |
| WO-2003002079-A1 | COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS | L'OREAL (FR) | 2003-01-09 | — | — | WO | disclosed |
| WO-2003002072-A1 | COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS | L'ORÉAL (FR) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203179-A1 | Especially suitable for inhibiting the development of body odour in men | SRD5A1, SRD5A2, PON1 | LTA4H 312/4885NR1H2 613/4885BAX 3159/4885 |
| US-20120328541-A1 | Anti-radical agents | NOS3, GSTO1, TXN2 | LTA4H 577/4885NR1H2 782/4885BAX 141/4885 |
| US-20080305055-A1 | Anti-Radical Agents | NOS3, GSTO1, PTGS1 | LTA4H 427/4885NR1H2 978/4885BAX 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.