SCHEMBL6062253

SCHEMBL6062253

COc1cc(F)cc(F)c1Bc1cc(F)cc(F)c1OC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PDGFRB P09619 1/20 0.31
PDGFRA P16234 1/20 0.31
TUBB1 Q9H4B7 3/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6062168 0.90 HTR7 (0.31)
SCHEMBL6062371 0.85 TUBB1 (0.33) TUBB1
SCHEMBL5364888 0.84 TRPA1 (0.34) ALDH1A1LMNAGAAMAPTTUBB1
SCHEMBL5349594 0.84 HTR7 (0.33) ALDH1A1LMNAGAAMAPTPDGFRB
SCHEMBL5350586 0.83 TUBB1 (0.31) TUBB1
SCHEMBL6062908 0.83
SCHEMBL6062337 0.83 TAAR1 (0.36) ALDH1A1
SCHEMBL6063655 0.83 TUBB1 (0.33) TUBB1
SCHEMBL6063878 0.82 TRPA1 (0.33) LMNATUBB1
SCHEMBL6063669 0.82 ALDH1A1 (0.31) ALDH1A1LMNAGAAMAPTPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060264320-A1 Hydrophobization and silica for supported catalyst RODRIGUEZ GEORGE 2006-11-23 US disclosed