SCHEMBL6062363

SCHEMBL6062363

CC(C)c1cc(CCc2ccccc2)ccc1Oc1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.50
POLB P06746 1/20 0.49
TAAR5 O14804 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
TTR P02766 1/20 0.42
ESR1 P03372 1/20 0.42
OPRK1 P41145 1/20 0.42
LTA4H P09960 1/20 0.41
NR1H2 P55055 1/20 0.41
BAX Q07812 1/20 0.41
KDM4E B2RXH2 1/20 0.41
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7263477 0.86 TAAR5 (0.48) TAAR5TAAR1LTA4H
SCHEMBL6063658 0.83 LTA4H (0.45) TAAR5TAAR1LTA4H
SCHEMBL9715457 0.79 MEN1 (0.46) TAAR5TAAR1ESR1LTA4HNR1H2
SCHEMBL6062365 0.78 F2 (0.50) F2POLBTAAR5TAAR1
SCHEMBL6062245 0.77 LTA4H (0.68) F2POLBESR1LTA4HNR1H2
SCHEMBL24196084 0.77 CYP1A2 (0.46) TTRLTA4H
SCHEMBL6061211 0.76 HTR2A (0.50) ESR1LTA4HNR1H2BAX
SCHEMBL3682170 0.75 PPARG (0.39) TAAR5TAAR1FFAR1
SCHEMBL3682167 0.75 PPARG (0.39) TAAR5TAAR1FFAR1
SCHEMBL465786 0.75 HTR2A (0.47) ESR1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003002080-A1 COMPOSITIONS CONTAINING A DERIVATIVE OF HYDROXYDIPHENYL ETHER INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002078-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002081-A1 COMPOSITION COMPRISING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002079-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002072-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'ORÉAL (FR) 2003-01-09 WO claimed
US-7105577-B2 for finishing of undyed and dyed or printed fibre materials; treatment of skin, mucous membrane or hair, hard surfaces, oral care; detergent CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-09-12 US disclosed
WO-2003002080-A1 COMPOSITIONS CONTAINING A DERIVATIVE OF HYDROXYDIPHENYL ETHER INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO disclosed
WO-2003002078-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO disclosed
WO-2003002081-A1 COMPOSITION COMPRISING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO disclosed
WO-2003002072-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'ORÉAL (FR) 2003-01-09 WO disclosed
WO-2003002079-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO disclosed