SCHEMBL465786

SCHEMBL465786

Cc1ccc(Oc2ccc(O)cc2)c(C(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.47
SLC6A4 P31645 3/20 0.47
KCNH2 Q12809 2/20 0.47
TRPA1 O75762 1/20 0.46
LMNA P02545 1/20 0.46
CHRM1 P11229 1/20 0.46
SLC6A2 P23975 1/20 0.46
ADRA1A P35348 1/20 0.46
HTR2B P41595 1/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
LTA4H P09960 2/20 0.41
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15719318 0.95 HTR2A (0.44) HTR2ASLC6A4KCNH2TRPA1LMNA
SCHEMBL9715457 0.88 MEN1 (0.46) HTR2ASLC6A4KCNH2MEN1KMT2A
SCHEMBL6149689 0.87 LMNA (0.50) HTR2ASLC6A4KCNH2TRPA1LMNA
SCHEMBL465518 0.82 MEN1 (0.48) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL11010571 0.82 LMNA (0.48) HTR2ASLC6A4KCNH2TRPA1LMNA
SCHEMBL6063658 0.80 LTA4H (0.45) TRPA1LTA4H
SCHEMBL8634177 0.79 KMT2A (0.39) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL6284868 0.78 LMNA (0.50) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL28091759 0.78 ESR2 (0.46) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL8638602 0.78 LTA4H (0.59) SLC6A4LMNASLC6A2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160295863-A1 FUNGICIDAL PENFLUFEN MIXTURES LANXESS DEUTSCHLAND GMBH (DE) 2016-10-13 US claimed
US-20140088041-A1 FUNGICIDAL PENFLUFEN MIXTURES LANXESS DEUTSCHLAND GMBH (DE) 2014-03-27 US claimed
EP-2632267-A1 FUNGICIDAL PENFLUFEN MIXTURES Lanxess Deutschland GmbH (DE) 2013-09-04 EP claimed
WO-2012076699-A1 BIOCIDE MICROCAPSULE FORMULATIONS CONTAINING STABILISED IODINE-CONTAINING COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2012-06-14 WO claimed
EP-2462805-A1 Formulations containing stabilised compounds containing iodine LANXESS Deutschland GmbH (DE) 2012-06-13 EP claimed
WO-2012055674-A1 FUNGICIDAL PENFLUFEN MIXTURES LANXESS DEUTSCHLAND GMBH (DE) 2012-05-03 WO claimed
EP-2443928-A1 Fungicide penflufen mixtures LANXESS Deutschland GmbH (DE) 2012-04-25 EP claimed
US-12604900-B2 Penflufen as a wood preservative against wood- destroying basidiomy cetes LANXESS DEUTSCHLAND GMBH (DE) 2026-04-21 US disclosed
US-20260053140-A1 Fungicide Mixtures LANXESS DEUTSCHLAND GMBH (DE) 2026-02-26 US disclosed
US-12369584-B2 Fungicide mixtures LANXESS DEUTSCHLAND GMBH (DE) 2025-07-29 US disclosed
EP-3808178-B1 FUNGICIDE MIXTURES LANXESS DEUTSCHLAND GMBH (DE) 2024-12-11 EP disclosed
US-20230337680-A1 PENFLUFEN AS A WOOD PRESERVATIVE AGAINST WOOD-DESTROYING BASIDIOMYCETES LANXESS DEUTSCHLAND GMBH (DE) 2023-10-26 US disclosed
EP-3725155-B1 ANTIFUNGAL WALLBOARDS LANXESS DEUTSCHLAND GMBH (DE) 2023-09-13 EP disclosed
WO-2006012996-A1 5-IODOTETRAZOLES LANXESS DEUTSCHLAND GMBH (DE) 2006-02-09 WO disclosed
EP-1569920-A2 CYCLOPENTA C]ISOXAZOLE-3-AMINES USED AS PROTECTIVE AGENTS FOR MATERIALS LANXESS Deutschland GmbH (DE) 2005-09-07 EP disclosed
EP-1569894-A2 2-OXYAMINO-1-CYCLOPENTENE-1-NITRILES AS MATERIAL PROTECTIVE AGENTS LANXESS Deutschland GmbH (DE) 2005-09-07 EP disclosed
EP-1527054-A1 SUBSTITUTED THIAZINES AS MATERIAL PROTECTING AGENTS Lanxess Deutschland GmbH (DE) 2005-05-04 EP disclosed
WO-2004050644-A2 CYCLOPENTA[C]ISOXAZOLE-3-AMINES USED AS PROTECTIVE AGENTS FOR MATERIALS LANXESS DEUTSCHLAND GMBH (DE) 2004-06-17 WO disclosed
WO-2004050608-A2 2-OXYAMINO-1-CYCLOPENTENE-1-NITRILES AS MATERIAL PROTECTIVE AGENTS LANXESS DEUTSCHLAND GMBH (DE) 2004-06-17 WO disclosed
WO-2004013113-A1 SUBSTITUTED THIAZINES AS MATERIAL PROTECTING AGENTS LANXESS DEUTSCHLAND GMBH (DE) 2004-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337680-A1 PENFLUFEN AS A WOOD PRESERVATIVE AGAINST WOOD-DESTROYING BASIDIOMYCETES BLVRB, DCXR, PAH HTR2A 1690/4885SLC6A4 2898/4885KCNH2 2087/4885
US-20140088041-A1 FUNGICIDAL PENFLUFEN MIXTURES CYP3A43, CYP2F1, CYP4F3 HTR2A 2178/4885SLC6A4 2138/4885KCNH2 1990/4885
US-12604900-B2 Penflufen as a wood preservative against wood- destroying basidiomy cetes PSENEN, CMA1, PSEN1 HTR2A 1703/4885SLC6A4 1856/4885KCNH2 484/4885
US-20160295863-A1 FUNGICIDAL PENFLUFEN MIXTURES CYP3A43, PFAS, CAT HTR2A 2131/4885SLC6A4 1735/4885KCNH2 2081/4885
US-20260053140-A1 Fungicide Mixtures TTL, MASTL, CYP51A1 HTR2A 4048/4885SLC6A4 4402/4885KCNH2 1038/4885
US-12369584-B2 Fungicide mixtures TTL, TH, DDT HTR2A 4692/4885SLC6A4 3999/4885KCNH2 1214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.