Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063678 | 1.00 | PREP (0.64) | PREPDPP4 | |
| SCHEMBL6062493 | 1.00 | PREP (0.64) | PREPDPP4 | |
| SCHEMBL8271402 | 0.81 | PREP (0.61) | PREPDPP4 | |
| SCHEMBL2970576 | 0.81 | PREP (0.61) | PREPDPP4 | |
| SCHEMBL8272077 | 0.81 | PREP (0.61) | PREPDPP4 | |
| SCHEMBL6062550 | 0.77 | PREP (0.41) | PREPDPP4 | |
| SCHEMBL6062543 | 0.77 | PREP (0.41) | PREPDPP4 | |
| SCHEMBL6063191 | 0.77 | PREP (0.41) | PREPDPP4 | |
| SCHEMBL12495677 | 0.76 | ACE (0.44) | PREPDPP4 | |
| Trifluoroacetic Acid SCHEMBL1730734 | 0.76 | PREP (0.48) | PREPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008957-B2 | Bicyclic cyanoheterocycles, process for their preparation and their use as medicaments | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-03-07 | — | — | US | disclosed |
| US-20050059716-A1 | Novel bicyclic cyanoheterocycles, process for their preparation and their use as medicaments | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059716-A1 | Novel bicyclic cyanoheterocycles, process for their preparation and their use as medicaments | CYP11B2, GOT2, CYP11B1 | PREP 1516/4885DPP4 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.