SCHEMBL606253

SCHEMBL606253

CCc1cccc(C)c1C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.43
GABRB2 P47870 4/20 0.43
ALDH1A1 P00352 5/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PTGS2 P35354 1/20 0.36
TRIM24 O15164 1/20 0.35
TRIM33 Q9UPN9 1/20 0.35
NLRP3 Q96P20 1/20 0.35
PIM1 P11309 1/20 0.35
PIM3 Q86V86 1/20 0.35
HTT P42858 1/20 0.35
PKM P14618 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320588 0.86 GABRA1 (0.50) GABRA1GABRB2ALDH1A1TDP1MEN1
SCHEMBL7090370 0.85 GABRA1 (0.44) GABRA1GABRB2ALDH1A1MEN1KMT2A
SCHEMBL605657 0.83 ALDH1A1 (0.43) GABRA1GABRB2ALDH1A1TSHRTDP1
SCHEMBL28632291 0.83 GAA (0.39) TSHRTDP1PTGS2HSD17B10CYP3A4
SCHEMBL2775950 0.83 GABRA1 (0.43) GABRA1GABRB2ALDH1A1TDP1PTGS2
SCHEMBL66979 0.81 ALDH1A1 (0.52) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL10971364 0.81 GABRA1 (0.41) GABRA1GABRB2ALDH1A1TDP1MEN1
SCHEMBL6353982 0.80 IGF1R (0.39) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL8791921 0.80 GABRA1 (0.43) GABRA1GABRB2ALDH1A1TSHRTDP1
SCHEMBL7745169 0.80 BID (0.45) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-3444238-B1 PROCESS FOR PREPARING DIFLUOROMETHYLENE COMPOUNDS SATO PHARMA (JP) 2021-12-08 EP disclosed
EP-1890992-B1 AN ENRICHMENT PROCESS USING COMPOUNDS USEFUL IN A POLYESTER PROCESS GRUPO PETROTEMEX SA DE CV (MX) 2019-10-23 EP disclosed
EP-1888498-B1 A PROCESS TO PRODUCE AN ENRICHMENT FEED GRUPO PETROTEMEX SA DE CV (MX) 2019-06-26 EP disclosed
EP-1888497-B1 A PROCESS TO PRODUCE AN ENRICHED COMPOSITION THROUGH THE USE OF A CATALYST REMOVAL ZONE AND AN ENRICHMENT ZONE GRUPO PETROTEMEX SA DE CV (MX) 2019-04-17 EP disclosed
EP-2066612-B1 A PROCESS TO PRODUCE AN ENRICHMENT FEED GRUPO PETROTEMEX SA DE CV (MX) 2018-08-01 EP disclosed
US-10029973-B2 Optimized liquid-phase oxidation GROPO PETROTEMEX, S.A. DE C.V. (MX) 2018-07-24 US disclosed
US-20180072648-A1 OPTIMIZED LIQUID-PHASE OXIDATION GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2018-03-15 US disclosed
EP-2316566-B1 Bubble column reactor for gas-liquid exchange reactions GRUPO PETROTEMEX SA DE CV (MX) 2017-11-22 EP disclosed
EP-1791800-B1 OPTIMIZED LIQUID-PHASE OXIDATION GRUPO PETROTEMEX SA DE CV (MX) 2017-11-01 EP disclosed
US-5488117-A FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1996-01-30 US disclosed
EP-0685519-A1 Oligomeric HALS-phosphites and HALS-phosphonites as stabilizers CIBA-GEIGY AG (CH) 1995-12-06 EP disclosed
US-5428162-A For protecting organic materials against thermal, oxidative or light-induced degradation CIBA-GEIGY CORPORATION (US) 1995-06-27 US disclosed
EP-0648765-A1 Process for the production of 3-arylbenzofuranones CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
US-5405891-A Hindered amine light stabilizers CIBA-GEIGY CORPORATION (US) 1995-04-11 US disclosed
EP-0644190-A1 Benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1995-03-22 EP disclosed
US-5369159-A Heat, oxidation and radiation resistance for polymers CIBA-GEIGY CORPORATION (US) 1994-11-29 US disclosed
EP-0608198-A1 Cyclic diphenylacetonenitriles as stabilisers CIBA-GEIGY AG (CH) 1994-07-27 EP disclosed
EP-0601973-A1 Oligomeric HALS-phosphite and HALS-phosphonites as stabilizers CIBA-GEIGY AG (CH) 1994-06-15 EP disclosed
EP-0591102-A1 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-04-06 EP disclosed