SCHEMBL6062545

SCHEMBL6062545

COc1cc(F)c(Bc2c(F)ccc(OC)c2F)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 5/20 0.39
CYP1A1 P04798 3/20 0.37
CYP1B1 Q16678 3/20 0.37
CYP1A2 P05177 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
NQO2 P16083 3/20 0.37
TTR P02766 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.37
MYC P01106 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
NFE2L2 Q16236 2/20 0.36
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6062497 0.88 TUBB1 (0.40) TUBB1CYP1A2NFE2L2MEN1MAPT
SCHEMBL5355583 0.88 TUBB1 (0.43) TUBB1CA12CA1CA2CA7
SCHEMBL6063456 0.85 TUBB1 (0.44) TUBB1NFE2L2MEN1MAPTKMT2A
SCHEMBL6062913 0.83 TAAR1 (0.36) TUBB1CYP1A1CYP1B1CYP1A2NQO2
SCHEMBL6063832 0.83 TUBB1 (0.45) TUBB1NFE2L2MEN1MAPTKMT2A
SCHEMBL6063023 0.82 TUBB1 (0.38) TUBB1CYP1A2NFE2L2MEN1MAPT
SCHEMBL5366348 0.82 TUBB1 (0.40) TUBB1NFE2L2ALDH1A1LMNAMAPK1
SCHEMBL5354701 0.82 TUBB1 (0.40) TUBB1NFE2L2MEN1MAPTKMT2A
SCHEMBL6062151 0.82 TUBB1 (0.38) TUBB1NFE2L2TUBB4ATUBBTUBA3C
SCHEMBL5358129 0.82 TAAR1 (0.48) CYP1A1CYP1B1CYP1A2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060264320-A1 Hydrophobization and silica for supported catalyst RODRIGUEZ GEORGE 2006-11-23 US disclosed