SCHEMBL6062913

SCHEMBL6062913

COc1cc(F)c(Bc2c(F)ccc(C)c2F)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.36
CYP1A1 P04798 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP1B1 Q16678 1/20 0.34
AMY1A P0DUB6 1/20 0.34
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
TUBB1 Q9H4B7 1/20 0.31
NQO2 P16083 1/20 0.31
NFE2L2 Q16236 1/20 0.30
PRKAB2 O43741 1/20 0.30
PRKAG1 P54619 1/20 0.30
PRKAA2 P54646 1/20 0.30
PRKAA1 Q13131 1/20 0.30
PRKAG3 Q9UGI9 1/20 0.30
PRKAG2 Q9UGJ0 1/20 0.30
PRKAB1 Q9Y478 1/20 0.30
PDE2A O00408 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6062545 0.83 TUBB1 (0.39) TAAR1CYP1A1CYP1A2CYP1B1ALDH1A1
SCHEMBL5353065 0.83 TAAR1 (0.38) TAAR1CYP1A1CYP1A2CYP1B1AMY1A
SCHEMBL6062440 0.82 RAPGEF4 (0.32)
SCHEMBL6063568 0.82 TUBB1 (0.30) TUBB1
SCHEMBL5352628 0.82 ACHE (0.35)
SCHEMBL5358129 0.82 TAAR1 (0.48) TAAR1CYP1A1CYP1A2CYP1B1ALDH1A1
SCHEMBL6062858 0.80 TUBB1 (0.35) MAPTHTTTUBB1
SCHEMBL5346533 0.79 TAAR1 (0.38) TAAR1CYP1A1CYP1A2CYP1B1ALDH1A1
SCHEMBL6062526 0.79 TUBB1 (0.42) HTTTUBB1NFE2L2
SCHEMBL5363833 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060264320-A1 Hydrophobization and silica for supported catalyst RODRIGUEZ GEORGE 2006-11-23 US disclosed