SCHEMBL6062872

SCHEMBL6062872

C=CCCCCC([SiH3])(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063073 0.98 TSHR (0.43) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6064145 0.98 TSHR (0.43) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6064121 0.98 TSHR (0.43) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6063300 0.93 ALDH1A1 (0.39) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL6063939 0.84 TSHR (0.33) TSHRALDH1A1
SCHEMBL8514201 0.77 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL2909990 0.76 TSHR (0.46) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL8513396 0.75 TSHR (0.41) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL8514659 0.75 TSHR (0.41) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL8510548 0.75 TSHR (0.41) TSHRALDH1A1LMNALPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2691464-B1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE MOMENTIVE PERFORMANCE MAT INC (US) 2019-01-09 EP claimed
US-8859674-B2 Moisture curable silylated polymer compositions with improved adhesion to concrete MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-14 US claimed
EP-2691464-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE Momentive Performance Materials Inc. (US) 2014-02-05 EP claimed
WO-2012135443-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-10-04 WO claimed
US-20120251832-A1 Moisture Curable Silylated Polymer Compositions With Improved Adhesion to Concrete MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-10-04 US claimed
EP-2691464-B1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE MOMENTIVE PERFORMANCE MAT INC (US) 2019-01-09 EP disclosed
US-8859674-B2 Moisture curable silylated polymer compositions with improved adhesion to concrete MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-14 US disclosed
EP-2691464-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE Momentive Performance Materials Inc. (US) 2014-02-05 EP disclosed
WO-2012135443-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-10-04 WO disclosed
US-20120251832-A1 Moisture Curable Silylated Polymer Compositions With Improved Adhesion to Concrete MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-10-04 US disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed