SCHEMBL6063300

SCHEMBL6063300

C=CCCCC([SiH3])(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
TSHR P16473 3/20 0.39
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6062872 0.93 TSHR (0.39) ALDH1A1LMNATSHRABCC4MAPT
SCHEMBL6064121 0.91 TSHR (0.43) ALDH1A1LMNATSHRABCC4MAPT
SCHEMBL6064145 0.91 TSHR (0.43) ALDH1A1LMNATSHRABCC4MAPT
SCHEMBL6063073 0.91 TSHR (0.43) ALDH1A1LMNATSHRABCC4MAPT
SCHEMBL6063939 0.86 TSHR (0.33) ALDH1A1TSHR
SCHEMBL6063912 0.78 TSHR (0.41) ALDH1A1LMNATSHR
SCHEMBL8513934 0.74 ALDH1A1 (0.37) ALDH1A1LMNATSHR
SCHEMBL2448884 0.74 ALDH1A1 (0.33) ALDH1A1
SCHEMBL2954860 0.72 TSHR (0.41) ALDH1A1LMNATSHRABCC4MAPT
SCHEMBL1125587 0.71 TSHR (0.55) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed