SCHEMBL6064121

SCHEMBL6064121

C=CCCCCCCCCC([SiH3])(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
LPAR3 Q9UBY5 2/20 0.33
MAPT P10636 2/20 0.33
ABCC4 O15439 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33
TRPA1 O75762 1/20 0.31
USP2 O75604 1/20 0.30
CYP3A4 P08684 1/20 0.30
RECQL P46063 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064145 1.00 TSHR (0.43) TSHRALDH1A1LMNALPAR3MAPT
SCHEMBL6063073 1.00 TSHR (0.43) TSHRALDH1A1LMNALPAR3MAPT
SCHEMBL6062872 0.98 TSHR (0.39) TSHRALDH1A1LMNALPAR3MAPT
SCHEMBL6063300 0.91 ALDH1A1 (0.39) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL6063939 0.82 TSHR (0.33) TSHRALDH1A1
SCHEMBL2909990 0.78 TSHR (0.46) TSHRALDH1A1LMNALPAR3MAPT
SCHEMBL8510548 0.78 TSHR (0.41) TSHRALDH1A1LMNALPAR3MAPT
SCHEMBL8514659 0.78 TSHR (0.41) TSHRALDH1A1LMNALPAR3MAPT
SCHEMBL8514127 0.78 TSHR (0.41) TSHRALDH1A1LMNALPAR3MAPT
SCHEMBL8513317 0.78 TSHR (0.41) TSHRALDH1A1LMNALPAR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed