SCHEMBL6063160

SCHEMBL6063160

CCCCC(C(=O)OC(C)C)C(=O)OC(C)C

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
CA2 P00918 4/20 0.44
CA1 P00915 4/20 0.44
FAAH O00519 1/20 0.40
TSHR P16473 3/20 0.39
CYP3A4 P08684 1/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPK1 P28482 1/20 0.39
ALOX15 P16050 1/20 0.38
POLB P06746 1/20 0.38
CTSK P43235 1/20 0.38
ZDHHC7 Q9NXF8 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8469134 0.92 LMNA (0.46) LMNACA2CA1FAAHTSHR
SCHEMBL7640123 0.92 LMNA (0.55) LMNACA1FAAHZDHHC7
SCHEMBL28665609 0.92 LMNA (0.55) LMNACA1FAAHZDHHC7
SCHEMBL27346868 0.92 LMNA (0.55) LMNACA1FAAHZDHHC7
SCHEMBL7633397 0.90 LMNA (0.44) LMNACA2CA1FAAHTSHR
SCHEMBL6064146 0.86 LMNA (0.42) LMNACA2CA1FAAHTSHR
SCHEMBL7644128 0.84 FAAH (0.50) LMNACA1FAAHZDHHC7
SCHEMBL7641729 0.83 FAAH (0.53) LMNACA1FAAHMAPK1ZDHHC7
SCHEMBL28729253 0.83 LMNA (0.50) LMNAFAAHZDHHC7
SCHEMBL7637304 0.83 FAAH (0.53) LMNACA1FAAHMAPK1ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104910001-A Synthetic method of 5-chloro-1-indanone XU WEI 2015-09-16 CN claimed
CN-101337874-B Method for preparing indanone compounds SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) 2011-12-14 CN claimed
CN-101337874-A Method for preparing indanone compounds SHANGHAI CHEMICAL ACADEMY (CN) 2009-01-07 CN claimed
CN-109694420-A Catalyst system and pre-polymerized catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2019-04-30 CN disclosed
CN-101337874-B Method for preparing indanone compounds SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) 2011-12-14 CN disclosed
CN-101337874-A Method for preparing indanone compounds SHANGHAI CHEMICAL ACADEMY (CN) 2009-01-07 CN disclosed
CN-1283673-C Solid catalyst component for olefin polymerization IDEMITSU PETROCHEMICAL CO (JP) 2006-11-08 CN disclosed
US-7081427-B2 Solid catalyst component for olefin polymerization IDEMITSU KOSAN CO., LTD. (JP) 2006-07-25 US disclosed
CN-1561346-A Solid catalyst component for olefin polymerization IDEMITSU PETROCHEMICAL CO (JP) 2005-01-05 CN disclosed
US-20040102310-A1 Solid catalyst component for olefin polymerization IDEMITSU KOSAN CO., LTD. (JP) 2004-05-27 US disclosed
EP-1396503-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-03-10 EP disclosed