Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063160 | 0.92 | LMNA (0.48) | LMNACA2MAPK1CA1POLB | |
| SCHEMBL28729253 | 0.91 | LMNA (0.50) | LMNAACE2GPR84FFAR1MAPT | |
| SCHEMBL29455985 | 0.88 | CHRM1 (0.44) | LMNACA2MAPK1ACE2GPR84 | |
| SCHEMBL7633397 | 0.86 | LMNA (0.44) | LMNACA2MAPK1CA1POLB | |
| SCHEMBL6910766 | 0.85 | CA2 (0.47) | CA2MAPK1CA1ACE2GPR84 | |
| SCHEMBL7640123 | 0.84 | LMNA (0.55) | LMNACA1ACE2GPR84FFAR1 | |
| SCHEMBL27346868 | 0.84 | LMNA (0.55) | LMNACA1ACE2GPR84FFAR1 | |
| SCHEMBL28665609 | 0.84 | LMNA (0.55) | LMNACA1ACE2GPR84FFAR1 | |
| SCHEMBL28899060 | 0.82 | CYP1A2 (0.42) | LMNATSHR | |
| SCHEMBL28928870 | 0.82 | TSHR (0.33) | LMNAACE2GPR84FFAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920461-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montell Technology Company bv (NL) | 1999-06-09 | — | — | EP | claimed |
| WO-1998056834-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-12-17 | — | — | WO | claimed |