Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347841 | 0.85 | IDO1 (0.43) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL515164 | 0.81 | IDO1 (0.50) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL8538736 | 0.80 | AKR1B1 (0.40) | IDO1P2RX7 | |
| SCHEMBL9861905 | 0.79 | GABRA1 (0.45) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL10949699 | 0.77 | MAOB (0.46) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL7645348 | 0.76 | IDO1 (0.42) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL10347842 | 0.76 | IDO1 (0.44) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL11620702 | 0.76 | IDO1 (0.44) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL456789 | 0.76 | IDO1 (0.44) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL10534539 | 0.75 | NOS3 (0.36) | IDO1ALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185128-B1 | CATALYTIC HYDRODESULFURIZATION OF ORTHO-AMINOBENZYL SULFIDES | Monsanto Company (US) | 1990-05-16 | — | — | EP | claimed |
| US-4806687-A | Catalytic hydrodesulfurization of ortho-aminobenzylsulfides | MONSANTO COMPANY (US) | 1989-02-21 | — | — | US | claimed |
| EP-0136995-B1 | PREPARATION OF 2-(METHYLTHIOMETHYL)-6-(TRIFLUOROMETHYL) ANILINE FROM ORTHO-AMINOBENZOTRIFLUORIDE | Monsanto Company (US) | 1987-10-28 | — | — | EP | claimed |
| EP-0185128-A1 | Catalytic hydrodesulfurization of ortho-aminobenzyl sulfides | Monsanto Company (US) | 1986-06-25 | — | — | EP | claimed |
| US-4578514-A | Synthesis of sulfilimines | MONSANTO COMPANY (US) | 1986-03-25 | — | — | US | claimed |
| US-4493755-A | Electrolytic preparation of orthoalkyl-2-halo-N-acylanilides | MONSANTO COMPANY (US) | 1985-01-15 | — | — | US | claimed |
| US-4404069-A | Electrolytic desulfurization of anilino sulfur compounds | MONSANTO COMPANY (US) | 1983-09-13 | — | — | US | claimed |
| US-7145035-B2 | Methods of ortho alkylation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-12-05 | — | — | US | disclosed |
| US-20040082793-A1 | Methods of ortho alkylation | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-04-29 | — | — | US | disclosed |
| EP-1368310-A2 | IMPROVED METHODS OF ORTHO ALKYLATION | E. I. du Pont de Nemours and Company (US) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002072540-A2 | IMPROVED METHODS OF ORTHO ALKYLATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-19 | — | — | WO | disclosed |
| EP-0511826-B1 | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-07-16 | — | — | EP | disclosed |
| US-5500405-A | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1996-03-19 | — | — | US | disclosed |
| US-4578514-A | Synthesis of sulfilimines | MONSANTO COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
| EP-0143768-A1 | Preparation of ortho-(alkylthiomethyl) anilines by catalytic sulfilimine rearrangement | Monsanto Company (US) | 1985-06-05 | — | — | EP | disclosed |
| EP-0136995-A2 | Preparation of 2-(methylthiomethyl)-6-(trifluoromethyl) aniline from ortho-aminobenzotrifluoride | Monsanto Company (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4496765-A | Preparation of 2-(methylthiomethyl)-6-(trifluoromethyl)aniline from ortho-aminobenzotrifluoride | MONSANTO COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| US-4493755-A | Electrolytic preparation of orthoalkyl-2-halo-N-acylanilides | MONSANTO COMPANY (US) | 1985-01-15 | — | — | US | disclosed |
| US-4440964-A | INTERMEDIATES FOR PREPARING SUBSTITUTED ANILINES | MONSANTO COMPANY (US) | 1984-04-03 | — | — | US | disclosed |
| US-4404069-A | Electrolytic desulfurization of anilino sulfur compounds | MONSANTO COMPANY (US) | 1983-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082793-A1 | Methods of ortho alkylation | CBR1, AOC2, CBR3 | IDO1 515/4885MAOB 497/4885ALDH1A1 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.